Results 31 to 40 of about 966,118 (275)
With nearly 8,000 cases in the United States per year, and 2,000 deaths annually, bacterial meningitis continues to be a significant source of morbidity and mortality. The principal pathogens are Neisseria meningitidis, Streptococcus pneumoniae, group B streptococci, and Hemophilus influenzae.
Division of Internal Medicine, University of Florida College of Medicine, Gainesville, Florida, USA ( host institution ) +1 more
openaire +3 more sources
ASSESSMENT OF THE DIAGNOSTIC AND PROGNOSTIC ROLE OF CEREBEROSPINAL FLUID INTERLEUKIN-8 LEVEL IN ADULT PATIENTS WITH MENINGITIS [PDF]
Meningitis necessitates immediate diagnosis and therapy. It is important to distingu- ish bacterial from aseptic meningitis, as this help to avoid complications and unnece- ssary antibiotic use.
LAMIAA ADEL +2 more
doaj +1 more source
Tuberculous meningitis: new tools and new approaches required [version 1; peer review: not peer reviewed] [PDF]
Tuberculous meningitis is the most severe form of tuberculosis and causes widespread mortality and morbidity. Understanding of the epidemiology and pathogenesis is incomplete, and the optimal diagnosis and treatment are poorly defined.
Thwaites, Guy +2 more
core +3 more sources
Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis
The cytological and biochemical examination of cerebrospinal fluid (CSF) has been used for the presumed diagnosis of bacterial meningitis until the final microbiological results are achieved.
Renan Barros Domingues +3 more
doaj +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis.
New biomarkers like procalcitonin and C-reactive protein may help design an accurate decision support tool used to identify children with pleocytosis at low or high risk of bacterial meningitis.
Fernandez, Catarina Livana +7 more
core +1 more source
Introduction Haemophilus influenzae is a human-specific Gram-negative bacterium responsible for respiratory tract infection, sepsis, and meningitis. The study aimed to investigate the epidemiology, serotype distribution, and mechanisms of beta-lactam ...
Marlena Kiedrowska +7 more
doaj +1 more source
Serum procalcitonin in viral and bacterial meningitis
Background: In children with meningitis, there is a difficulty to verify the etiology as viral or bacterial. Therefore, intensive research has been carried out to find new and rapid diagnostic methods for differentiating bacterial from viral meningitis ...
Usama M Alkholi +3 more
doaj +1 more source
PREDICTING NEUROLOGICAL COMPLICATIONS FOLLOWING ACUTE BACTERIAL MENINGITIS IN CHILDREN VERSUS ADULTS [PDF]
This study determined the predictors for neurological complications of bacterial meningitis in children versus adult patients. This is a prospective study that enrolled 155 Egyptian patients with suspected acute bacterial meningitis (80 children less ...
MOAZ HEIKEL +5 more
doaj +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source

