Comparative Analysis of Gram Stain, Culture and Bacterial Antigen Detection in Cerebrospinal Fluid Samples for Laboratory Diagnosis of Acute Bacterial Meningitis in Pediatric Population in A Tertiary Care Hospital [PDF]
Acute bacterial meningitis (ABM) is a life threatening infection in children, associated with long term complications and high mortality rate.1,2 Gram staining and culture are routinely used for diagnosis of ABM.
V. Dillirani +3 more
core +1 more source
With nearly 8,000 cases in the United States per year, and 2,000 deaths annually, bacterial meningitis continues to be a significant source of morbidity and mortality. The principal pathogens are Neisseria meningitidis, Streptococcus pneumoniae, group B streptococci, and Hemophilus influenzae.
Division of Internal Medicine, University of Florida College of Medicine, Gainesville, Florida, USA ( host institution ) +1 more
openaire +3 more sources
Clinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis.
New biomarkers like procalcitonin and C-reactive protein may help design an accurate decision support tool used to identify children with pleocytosis at low or high risk of bacterial meningitis.
Fernandez, Catarina Livana +16 more
core +1 more source
ASSESSMENT OF THE DIAGNOSTIC AND PROGNOSTIC ROLE OF CEREBEROSPINAL FLUID INTERLEUKIN-8 LEVEL IN ADULT PATIENTS WITH MENINGITIS [PDF]
Meningitis necessitates immediate diagnosis and therapy. It is important to distingu- ish bacterial from aseptic meningitis, as this help to avoid complications and unnece- ssary antibiotic use.
LAMIAA ADEL +2 more
doaj +1 more source
Performance of lactate in discriminating bacterial meningitis from enteroviral meningitis
The cytological and biochemical examination of cerebrospinal fluid (CSF) has been used for the presumed diagnosis of bacterial meningitis until the final microbiological results are achieved.
Renan Barros Domingues +3 more
doaj +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Bacterial meningitis: current therapy and possible future treatment options [PDF]
Despite targeted therapy, case-fatality rates and neurologic sequelae of bacterial meningitis remain unacceptably high. The poor outcome is mainly due to secondary systemic and intracranial complications. These complications seem to be both a consequence
Grandgirard, Denis +9 more
core +1 more source
Introduction Haemophilus influenzae is a human-specific Gram-negative bacterium responsible for respiratory tract infection, sepsis, and meningitis. The study aimed to investigate the epidemiology, serotype distribution, and mechanisms of beta-lactam ...
Marlena Kiedrowska +7 more
doaj +1 more source
Utility of cerebrospinal fluid cortisol level in acute bacterial meningitis
Background: Meningitis remains a serious clinical problem in developing as well as developed countries. Delay in diagnosis and treatment results in significant morbidity and mortality.
Anish Mehta +4 more
doaj +1 more source
PREDICTING NEUROLOGICAL COMPLICATIONS FOLLOWING ACUTE BACTERIAL MENINGITIS IN CHILDREN VERSUS ADULTS [PDF]
This study determined the predictors for neurological complications of bacterial meningitis in children versus adult patients. This is a prospective study that enrolled 155 Egyptian patients with suspected acute bacterial meningitis (80 children less ...
MOAZ HEIKEL +5 more
doaj +1 more source

