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Meningitis [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1984
Publisher Summary This chapter describes the clinical aspects of meningitis. In most patients who prove to have meningitis, the need for lumbar puncture is evident on first assessment. Meningeal signs are often found in patients with pneumonia or with acute tonsillitis, in patients generally with high fever, and occasionally in certain specific ...
openaire   +3 more sources

From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]

open access: yes, 2017
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core   +3 more sources

An evaluation of an influenza vaccination campaign targeting pregnant women in 27 clinics in two provinces of South Africa, 2015 – 2018

open access: yesBMC Health Services Research, 2021
Introduction Despite prioritization, routine antenatal influenza vaccine coverage is
Kate Bishop   +12 more
doaj   +1 more source

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]

open access: yes, 2019
The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D.   +25 more
core   +2 more sources

Genomic characterization of Haemophilus influenzae: a focus on the capsule locus

open access: yesBMC Genomics, 2019
Background Haemophilus influenzae (Hi) can cause invasive diseases such as meningitis, pneumonia, or sepsis. Typeable Hi includes six serotypes (a through f), each expressing a unique capsular polysaccharide.
Caelin C. Potts   +11 more
doaj   +1 more source

Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

open access: yesBMC Infectious Diseases, 2019
Background We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls.
Fahima Moosa   +10 more
doaj   +1 more source

Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing. [PDF]

open access: yes, 2019
Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral ...
Beyene, T   +5 more
core   +1 more source

Subjective Fatigue in Children With Unaided and Aided Unilateral Hearing Loss

open access: yesThe Laryngoscope, Volume 133, Issue 1, Page 189-198, January 2023., 2023
Objectives Fatigue is frequently observed in children with chronic diseases and can affect the quality of life (QoL). However, research in children with unilateral hearing loss (UHL) is scarce. Subsequently, no studies investigated the effects of hearing aids on fatigue in children.
Kim H. E. Bakkum   +4 more
wiley   +1 more source

Whole genome sequencing for investigations of meningococcal outbreaks in the United States: a retrospective analysis

open access: yesScientific Reports, 2018
Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S.
Melissa J. Whaley   +10 more
doaj   +1 more source

Genetic Features of a Representative Panel of 110 Meningococcal B Isolates to Assess the Efficacy of Meningococcal B Vaccines

open access: yesmSphere, 2022
Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi   +8 more
doaj   +1 more source

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