Results 21 to 30 of about 494,505 (356)

Genomic characterization of Haemophilus influenzae: a focus on the capsule locus

BMC Genomics, 2019
Background Haemophilus influenzae (Hi) can cause invasive diseases such as meningitis, pneumonia, or sepsis. Typeable Hi includes six serotypes (a through f), each expressing a unique capsular polysaccharide.
Caelin C. Potts, Nadav Topaz, Lorraine D. Rodriguez-Rivera, Fang Hu, How-Yi Chang, Melissa J. Whaley, Susanna Schmink, Adam C. Retchless, Alexander Chen, Edward Ramos, Gregory H. Doho, Xin Wang   +11 more
doaj   +1 more source

Impact of a mass vaccination campaign against a meningitis epidemic in a refugee camp. [PDF]

, 1996
Serogroup A meningococcus epidemics occurred in refugee populations in Zaire in August 1994. The paper analyses the public health impact of a mass vaccination campaign implemented in a large refugee camp.
Blok, L, Boelaert, M, Haelterman, E, Henkens, M, Suetens, C, Toole, M J   +5 more
core   +2 more sources

An evaluation of an influenza vaccination campaign targeting pregnant women in 27 clinics in two provinces of South Africa, 2015 – 2018

BMC Health Services Research, 2021
Introduction Despite prioritization, routine antenatal influenza vaccine coverage is
Kate Bishop, Meredith McMorrow, Susan Meiring, Sibongile Walaza, Liza Rossi, Sarona Mhlanga, Stefano Tempia, Azwifarwi Mathunjwa, Jackie Kleynhans, Grace D. Appiah, Johanna M. McAnerney, Heather J. Zar, Cheryl Cohen   +12 more
doaj   +1 more source

Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]

, 2017
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla, Caraffa, Emanuela, Ciardi, Rosa Maria, Colistra, Davide, DI BIASI, Claudio, Lichtner, Miriam, Mancarella, Cristina, Mascia, Claudia, Mastroianni, Claudio Maria, Mengoni, Fabio, Paglia, Maria Grazia, Vita, Serena, Vullo, Vincenzo   +12 more
core   +4 more sources

Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]

, 2018
Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla, Caraffa, Emanuela, Ciardi, Maria Rosa, Lichtner, Miriam, Massetti, Anna Paola, Mastroianni, Claudio Maria, Russo, Gianluca, Vita, Serena, Vullo, Vincenzo   +8 more
core   +1 more source

Whole genome sequencing for investigations of meningococcal outbreaks in the United States: a retrospective analysis

Scientific Reports, 2018
Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S.
Melissa J. Whaley, Sandeep J. Joseph, Adam C. Retchless, Cecilia B. Kretz, Amy Blain, Fang Hu, How-Yi Chang, Sarah A. Mbaeyi, Jessica R. MacNeil, Timothy D. Read, Xin Wang   +10 more
doaj   +1 more source

Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]

, 2014
Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G., Lahni, Patrick M., Ma, William, Standage, Stephen W., Wheeler, Derek S., Wong, Hector R.   +5 more
core   +1 more source

Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

BMC Infectious Diseases, 2019
Background We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls.
Fahima Moosa, Mignon du Plessis, Nicole Wolter, Maimuna Carrim, Cheryl Cohen, Claire von Mollendorf, Sibongile Walaza, Stefano Tempia, Halima Dawood, Ebrahim Variava, Anne von Gottberg   +10 more
doaj   +1 more source

The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016

BMC Medicine, 2023
Background Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies.
Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow, Florette Treurnicht, Nicole Wolter, Anne von Gottberg, Kathleen Kahn, Adam L. Cohen, Halima Dawood, Ebrahim Variava, Cheryl Cohen   +11 more
doaj   +1 more source

Genetic Features of a Representative Panel of 110 Meningococcal B Isolates to Assess the Efficacy of Meningococcal B Vaccines

mSphere, 2022
Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi, Margherita Bodini, Nadav Topaz, Vega Masignani, Kumaran Vadivelu, Henju Marjuki, Xin Wang, Laura Serino, Duccio Medini   +8 more
doaj   +1 more source