The age-related risk of co-existing meningitis in children with urinary tract infection [PDF]
, 2011 Objective: The primary aim of this study was to determine age-stratified rates of co-existing bacterial meningitis in children with urinary tract infection (UTI).
Clifford Vanessa +27 more
core +2 more sources
mSphere, 2022 Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi +8 more
doaj +1 more source
Lancet. Infectious Diseases (Print), 2020 Summary Background Xpert MTB/RIF Ultra (Xpert Ultra) might have higher sensitivity than its predecessor, Xpert MTB/RIF (Xpert), but its role in tuberculous meningitis diagnosis is uncertain. We aimed to compare Xpert Ultra with Xpert for the diagnosis of
Joseph Donovan +15 more
semanticscholar +1 more source
Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]
, 2009 During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg +20 more
core +2 more sources
Starting ART following cryptococcal meningitis:The optimal time has yet to be defined
Southern African Journal of HIV Medicine, 2013 Ever since the public sector rollout of antiretroviral therapy (ART) in 2004, the question of the optimal time to start ART following diagnosis of an opportunistic infection has aroused controversy among South African HIV clinicians and researchers.
T A Bicanic +3 more
doaj +1 more source
The burden of RSV-associated illness in children aged < 5 years, South Africa, 2011 to 2016
BMC Medicine, 2023 Background Vaccines and monoclonal antibodies to protect the very young infant against the respiratory syncytial virus (RSV)-associated illness are effective for limited time periods.
Jocelyn Moyes +11 more
doaj +1 more source
A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi. [PDF]
, 2014 OBJECTIVE: We have previously reported high ten-week mortality from cryptococcal meningitis in Malawian adults following treatment-induction with 800 mg oral fluconazole (57% [33/58]).
Allain, TJ +52 more
core +1 more source
BMC Public Health, 2021 Background Describing contact patterns is crucial to understanding infectious disease transmission dynamics and guiding targeted transmission mitigation interventions. Data on contact patterns in Africa, especially South Africa, are limited.
Jackie Kleynhans +13 more
doaj +1 more source
Bacterial meningitis: the role of transforming growth factor-Beta in innate immunity and secondary brain damage [PDF]
, 2007 Project 6 of the NCCR 'Neural Plasticity and Repair' focuses on mechanisms of immunity and tissue damage in autoimmune and infectious diseases of the central nervous system (CNS).
Malipiero, U +7 more
core +1 more source
Artificial Intelligence in Differential Diagnostics of Meningitis: A Nationwide Study
Diagnostics, 2021 Differential diagnosis between bacterial and viral meningitis is crucial. In our study, to differentiate bacterial vs. viral meningitis, three machine learning (ML) algorithms (multiple logistic regression (MLR), random forest (RF), and naïve-Bayes (NB))
Alexios-Fotios A. Mentis +6 more
doaj +1 more source