Results 61 to 70 of about 177,338 (265)

Spike detection in the wild: Screening of suspected temporal lobe epilepsy cases using a tailored 2‐channel wearable EEG

Epilepsia Open, EarlyView.
Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges, Joana Isabel Soares, Daniela Dias, Helena Cordeiro, Alberto Leal   +4 more
wiley   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Healthcare seeking behaviour for common infectious syndromes among people in three administrative regions of Johannesburg, South Africa, 2015: a cross-sectional study

The Pan African Medical Journal, 2019
INTRODUCTION: hospital-based surveillance programs only capture people presenting to facilities and may underestimate disease burden. We conducted a healthcare utilisation survey to characterise healthcare-seeking behaviour among people with common ...
Relebogile Mapuroma, Cheryl Cohen, Lazarus Kuonza, Alfred Musekiwa, Stefano Tempia, Akhona Tshangela, Claire von Mollendorf   +6 more
doaj   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch, Jakob Johann Schmidt, Daniel Delev, Roland Coras, Ingmar Blümcke, Ruth Beckervordersandforth   +5 more
wiley   +1 more source

Phylogenetic relationships and regional spread of meningococcal strains in the meningitis belt, 2011–2016Research in context

EBioMedicine, 2019
Background: Historically, the major cause of meningococcal epidemics in the meningitis belt of sub-Saharan Africa has been Neisseria meningitidis serogroup A (NmA), but the incidence has been substantially reduced since the introduction of a serogroup A ...
Nadav Topaz, Dominique A. Caugant, Muhamed-Kheir Taha, Ola Brønstad Brynildsrud, Nadia Debech, Eva Hong, Ala-Eddine Deghmane, Rasmata Ouédraogo, Sani Ousmane, Kadidja Gamougame, Berthe-Marie Njanpop-Lafourcade, Seydou Diarra, LeAnne M. Fox, Xin Wang   +13 more
doaj   +1 more source

Bacteremia in horses undergoing routine dental prophylaxis: Before, during, and after the procedure

Equine Veterinary Journal, EarlyView.
Abstract Background Transient bacteremia after dental procedures is well‐documented in the literature, but the prevalence and clinical significance in horses remains largely unexplored. Objectives To assess whether routine dental prophylaxis in clinically healthy horses is associated with detection of bacteria in blood, using culture and 16S rDNA ...
Allison Dockery, Canaan Whitfield‐Cargile, Vanessa Knopp, Taylor Sinay   +3 more
wiley   +1 more source

Outbreak of influenza A in a boarding school in South Africa, 2016

The Pan African Medical Journal, 2019
INTRODUCTION: We investigated an outbreak of influenza-like illness (ILI) at a boarding school in Eastern Cape Province, South Africa. We aimed to confirm the etiological agent, estimate attack rates and identify risk factors for illness.
Jackie Kleynhans, Florette Kathleen Treurnicht, Cheryl Cohen, Theesan Vedan, Mpho Seleka, Lwando Maki, Anne von Gottberg, Kerrigan McCarthy, Wayne Ramkrishna, Meredith McMorrow, Sibongile Walaza   +10 more
doaj   +1 more source

Diagnosis of bacteraemia in neonatal foals using 16S rRNA high‐throughput sequencing

Equine Veterinary Journal, EarlyView.
Abstract Background Sepsis is an important cause of morbidity and mortality in foals. Early diagnosis can improve outcome but is complicated by non‐specific clinical signs and delayed confirmation of infection via blood culture. Molecular assays represent a rapid and more sensitive alternative.
Flavie Payette, Alicia E. Long, Weiming Hu, Kyle Bittinger, Ahmed M. Moustafa, Darko Stefanovski, Michelle Abraham, Maia R. Aitken   +7 more
wiley   +1 more source

Characteristics of infections with ancestral, Beta and Delta variants of SARS-CoV-2 in the PHIRST-C community cohort study, South Africa, 2020-2021

BMC Infectious Diseases
Background Data on the characteristics of individuals with mild and asymptomatic infections with different SARS-CoV-2 variants are limited. We therefore compared the characteristics of individuals infected with ancestral, Beta and Delta SARS-CoV-2 ...
Cheryl Cohen, Jackie Kleynhans, Anne von Gottberg, Meredith L. McMorrow, Nicole Wolter, Jinal N. Bhiman, Jocelyn Moyes, Mignon du Plessis, Maimuna Carrim, Amelia Buys, Neil A. Martinson, Kathleen Kahn, Stephen Tollman, Limakatso Lebina, Floidy Wafawanaka, Jacques du Toit, Francesc Xavier Gómez-Olivé, Fatimah S. Dawood, Thulisa Mkhencele, for the PHIRST group, Stefano Tempia   +20 more
doaj   +1 more source

Neoplastic meningitis

Seminars in Neurology, 2004
Neoplastic meningitis (NM) is a common problem in neuro-oncology occurring in approximately 5% of all patients with cancer, and is the third most common site of CNS metastases. NM is a disease affecting the entire neuraxis, and therefore clinical manifestations are pleomorphic affecting the spine, cranial nerves, and cerebral hemispheres.
openaire   +7 more sources