Results 71 to 80 of about 343,717 (295)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen +4 more
wiley +1 more source
Neonatal meningitis caused by streptococcus pneumonia in Iran [PDF]
, 2015 Meningitis, pneumonia, and sepsis in newborns and young infants ...
Alaee, E. +3 more
core
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]
, 2012 WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black +21 more
core +3 more sources
Seminars in Neurology, 2004 Neoplastic meningitis (NM) is a common problem in neuro-oncology occurring in approximately 5% of all patients with cancer, and is the third most common site of CNS metastases. NM is a disease affecting the entire neuraxis, and therefore clinical manifestations are pleomorphic affecting the spine, cranial nerves, and cerebral hemispheres.
openaire +7 more sources
British Journal of Clinical Pharmacology, EarlyView.Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst +8 more
wiley +1 more source
Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
, 2012 SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source
Postgraduate Medical Journal, 1977 Summary Some of the main features of neonatal meningitis, studied in a defined population of infants, are reviewed. The incidence rate was twenty-six cases per 100 000 live-births. The case fatality rate was 43%. Gram-negative intestinal bacilli were the commonest infecting organisms.
openaire +2 more sources
Anaesthesia, 1993 Summary A case of meningitis following obstetric epidural anaesthesia is reported in which a group B, beta‐haemolytic streptococcus was isolated as the causative organism.
L, Davis, C, Hargreaves, P N, Robinson
openaire +2 more sources
Chiari I Malformation: Review and Update of Current Treatment Options
Clinical Anatomy, EarlyView.ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo +11 more
wiley +1 more source