The age-related risk of co-existing meningitis in children with urinary tract infection [PDF]
Objective: The primary aim of this study was to determine age-stratified rates of co-existing bacterial meningitis in children with urinary tract infection (UTI).
Clifford Vanessa +27 more
core +2 more sources
Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S.
Melissa J. Whaley +10 more
doaj +1 more source
Bacterial meningitis: the role of transforming growth factor-Beta in innate immunity and secondary brain damage [PDF]
Project 6 of the NCCR 'Neural Plasticity and Repair' focuses on mechanisms of immunity and tissue damage in autoimmune and infectious diseases of the central nervous system (CNS).
Malipiero, U +11 more
core +1 more source
Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 [PDF]
Background: Although meningitis is largely preventable, it still causes hundreds of thousands of deaths globally each year. WHO set ambitious goals to reduce meningitis cases by 2030, and assessing trends in the global meningitis burden can help track ...
Roberts, Thomas
core +3 more sources
The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016
Background Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies.
Jocelyn Moyes +11 more
doaj +1 more source
Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]
During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg +21 more
core +2 more sources
Correlation between CSF Glucose Level and Outcome on Adult Patients with Meningitis [PDF]
Background: Meningitis is an inflammatory response to infection of leptomeningeal cells and subarachnoid space. The severity of the inflammation could be reflected on the CSF glucose level.
Sari, Pramita
core +1 more source
Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa
Background We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls.
Fahima Moosa +10 more
doaj +1 more source
Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi +8 more
doaj +1 more source
Starting ART following cryptococcal meningitis:The optimal time has yet to be defined
Ever since the public sector rollout of antiretroviral therapy (ART) in 2004, the question of the optimal time to start ART following diagnosis of an opportunistic infection has aroused controversy among South African HIV clinicians and researchers.
T A Bicanic +3 more
doaj +1 more source

