Results 71 to 80 of about 374,791 (337)

Life After Invasive Meningococcal Disease: Insights from Survivors and Their Caregivers

Infectious Diseases and Therapy
Introduction Invasive meningococcal disease (IMD) has a low incidence but is a life-threatening illness that is preventable via vaccination. Even with treatment, up to 10–15% of cases are fatal, and many survivors may experience severe long-term sequelae.
Oscar Herrera-Restrepo, Nuzhat Afroz, Eliazar Sabater Cabrera, Matthew Reaney, France Ginchereau Sowell, Ramiya Kumar, Alicia Stillman, Patti Wukovits, Mariana Rodrigues, Sofia B. Pinto, Zeki Kocaata, Obinna Onwude   +11 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Cryptococcal meningitis in HIV-infected patients: a longitudinal study in Cambodia. [PDF]

, 2010
To describe the frequency of diagnosis of cryptococcosis among HIV-infected patients in Phnom Penh, Cambodia, at programme entry, to investigate associated risk factors, and to determine the incidence of cryptococcal ...
Amornkul, Antinori, Chariyalertsak, Chhin, Darras-Joly, Dromer, French, Havlir, Heyderman, Jarvis, Jongwutiwes, Kong, Lortholary, Louie, Madec, Manosuthi, Micol, Mirza, Moosa, Pichith, Powderly, Senya, Singh, Sorvillo, Sungkanuparph   +24 more
core   +2 more sources

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Molecular characterization of invasive meningococcal isolates in Burkina Faso as the relative importance of serogroups X and W increases, 2008–2012

BMC Infectious Diseases, 2018
Background Neisseria meningitidis serogroup A disease in Burkina Faso has greatly decreased following introduction of a meningococcal A conjugate vaccine in 2010, yet other serogroups continue to pose a risk of life-threatening disease. Capsule switching
Adam C. Retchless, Malika Congo-Ouédraogo, Dinanibè Kambiré, Jeni Vuong, Alex Chen, Fang Hu, Absetou Ky Ba, Abdoul-Salam Ouédraogo, Soumeya Hema-Ouangraoua, Jaymin C. Patel, Rasmata Ouédraogo Traoré, Lassana Sangaré, Xin Wang   +12 more
doaj   +1 more source

Vaccine implementation: Alaska 2017 [PDF]

, 2017
Bacterial meningitis is a serious disease that causes permanent dysfunction or death; adolescents and young adults carry the greatest risk. The national Advisory Committee on Immunization Practices (ACIP) has released vaccine recommendations that include
Hulstine, Amanda
core  

Intracerebral haemorrhage in a dog with steroid-responsive meningitis arteritis [PDF]

, 2017
A one-year and six-month-old female neutered Boxer dog was presented with a four-day history of pyrexia, lethargy and neck pain. An intracerebral haemorrhage and a mediastinal mass were identified.
Brocal, Josep, Gutierrez-Quintana, Rodrigo, Hammond, Gawain, José López, Roberto   +3 more
core   +1 more source

Adult and paediatric mortality patterns in a referral hospital in Liberia 1 year after the end of the war [PDF]

, 2009
The aim of this study was to describe and analyse hospital mortality patterns after the Liberian war. Data were collected retrospectively from January to July 2005 in a referral hospital in Monrovia, Liberia. The overall fatality rate was 17.2% (438/2543)
Accorsi, Ahmad, Atakouma, Ayoola, Becker, Becker, Berkley, Brigitte Vasset, Campagne, Campbell, Coghlan, Couper, Delaunay, Elisa Prados, Endeshaw, English, Evans, G/mariam, Gordon, Guha-Sapir, Harries, Harries, Helena Huerga, Idro, Johnson, Kingenberg, Laville, Macassa, Marsh, Mengistu, Ministry of Health and Social Welfare of Liberia, Mockenhaupt, Mohammed, Molyneux, Mudiavi, Nathoo, Njoh, Nyame, Ogun, Owusu-Oforia, O’Dempsey, Petit, Plange-Rhule, Reid, Reyburn, Robinson, Saissy, Sani, Savadogo, SBA, Soumare, Walker, Waller, WHO, Wiersinga, Williams, Wiredu, Wright, Youssef   +58 more
core   +2 more sources

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero, Marco Antonio Hernández Lepe, José de Jesús Manríquez Torres, Diego Daniel Aguirre‐Gómez, Natsuo Hayashi‐Mercado, Genaro Rodríguez Uribe, Tadeo Cerón, María Ruiz‐Gamboa, Jesús Alonso Gándara‐Mireles, Ismael Lares‐Asseff, Verónica Loera‐Castañeda, Jorge Alvelais‐Palacios, Lucrecia Arzamendi‐Cepeda, Lidia Magdalena Castañeda‐González, Adolfo García‐Barrón, Francisco Yamal Quiroz Herrera, Francisco González‐Salazar, Horacio Almanza‐Reyes   +17 more
wiley   +1 more source