Results 71 to 80 of about 380,344 (356)

The association between life events, social support, and antibody status following thymus-dependent and thymus-independent vaccinations in healthy young adults [PDF]

, 2005
This study determined whether stressful life events and social support were related to antibody status following both thymus-dependent and thymus-independent vaccinations. Life events in the previous year and customary social support were measured in 57
Burns, Victoria E., Carroll, Douglas, Drayson, Mark, Phillips, Anna C., Ring, Christopher   +4 more
core   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Molecular Identification of Meningitis/Septicemia Due to Streptococcus spp. in Greece (2015–2024)

Diagnostics
Background/Objectives: Meningitis due to the species Streptococcus is a severe central nervous system infection caused by various microorganisms belonging to Streptococcus spp.
Constantinos Karamalis, Athanasia Xirogianni, Stelmos Simantirakis, Marina Delegkou, Anastasia Papandreou, Georgina Tzanakaki   +5 more
doaj   +1 more source

Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing. [PDF]

, 2019
Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral ...
Beyene, T, Boulware, DR, Katende, A, Letang, E, Rajasingham, R, Wake, RM   +5 more
core   +1 more source

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

American Journal of Hematology, EarlyView.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler, Sunil Kumar Pusarla, Narinder Nangia, Miguel‐Angel Perales, Rafael F. Duarte, Andreas Grauer, Alessandro Rambaldi   +6 more
wiley   +1 more source

BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species

BMC Infectious Diseases, 2018
Background Bacterial meningitis is a life-threatening infection that remains a public health concern. Bacterial meningitis is commonly caused by the following species: Neisseria meningitidis, Streptococcus pneumoniae, Listeria monocytogenes, Haemophilus ...
Nadav Topaz, Dave Boxrud, Adam C. Retchless, Megan Nichols, How-Yi Chang, Fang Hu, Xin Wang   +6 more
doaj   +1 more source

Escherichia coli K1 RS218 Interacts with Human Brain Microvascular Endothelial Cells via Type 1 Fimbria Bacteria in the Fimbriated State [PDF]

, 2005
Escherichia coli K1 is a major gram-negative organism causing neonatal meningitis. E. coli K1 binding to and invasion of human brain microvascular endothelial cells (HBMEC) are a prerequisite for E.
Cai, M., di Cello, F., Khan, Naveed Ahmed, Kim, K.J., Kim, K.S., Shin, S., Teng, C.H., Xie, Y.   +7 more
core   +2 more sources

Comorbidities in Mild WAS/XLT Require Lifelong Follow‐Up and Consideration of Definitive Treatment

American Journal of Hematology, EarlyView.
Our study followed the clinical and biological course of 261 WAS/XLT patients, including 170 with a mild form of the disease. The occurrence of late complications even in mild patients confirms the importance of offering lifelong follow‐up and considering definitive treatment (HSCT/gene therapy) for all patients.
Coralie Mallebranche, Charline Miot, Mickael Alligon, Despina Moshous, Benedicte Neven, Vincent Barlogis, Virginie Courteille, Bénédicte Bruno, Marie Ouachée‐Chardin, Dalila Adjaoud, Yves Delneste, Olivier Bouaziz, Capucine Picard, Alain Fischer, Nizar Mahlaoui, Isabelle Pellier, Members of the CEREDIH French PID Study Group   +16 more
wiley   +1 more source

Cryptococcal infection of the ventriculoperitoneal shunt in an immunocompetent patient [PDF]

, 2016
Patient: Male, 52 Final Diagnosis: Cryptococcal ventriculoperitoneal shunt infection Symptoms: Confusion • fever • Lethargy Medication: Amphotericin B • Flucytosine Clinical Procedure: Ventriculoperitoneal shunt removal Specialty: Infectious disease ...
Foong, Kap Sum, Lee, Ashley, Vasquez, Gustavo   +2 more
core   +2 more sources

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero, Marco Antonio Hernández Lepe, José de Jesús Manríquez Torres, Diego Daniel Aguirre‐Gómez, Natsuo Hayashi‐Mercado, Genaro Rodríguez Uribe, Tadeo Cerón, María Ruiz‐Gamboa, Jesús Alonso Gándara‐Mireles, Ismael Lares‐Asseff, Verónica Loera‐Castañeda, Jorge Alvelais‐Palacios, Lucrecia Arzamendi‐Cepeda, Lidia Magdalena Castañeda‐González, Adolfo García‐Barrón, Francisco Yamal Quiroz Herrera, Francisco González‐Salazar, Horacio Almanza‐Reyes   +17 more
wiley   +1 more source