Results 61 to 70 of about 26,800 (175)

Complement Factor H‐Based Therapeutics: A Comprehensive Overview

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers, Emmy J. Buter, Richard B. Pouw   +2 more
wiley   +1 more source

Prevention of Meningococcal Disease: Knowledge, Attitudes, and Practices of General Practitioners and Primary Care Pediatricians in South Italy

Vaccines
Background: The purpose of this study was to evaluate the knowledge, attitude, and current practices about prevention of meningococcal disease among general practitioners (GPs) and primary care pediatricians (PCPs) in Italy.
Silvia Angelillo, Concetta Paola Pelullo, Francesca Licata, Raffaele Lanzano, Francesco Napolitano, Gabriella Di Giuseppe   +5 more
doaj   +1 more source

Treatment of Meningococcal Disease [PDF]

Journal of Adolescent Health, 2016
Meningococcal disease is a life-threatening infection that may progress rapidly, even after appropriate treatment has commenced. Early suspicion of the diagnosis is vital so that parenteral antibiotic treatment can be administered as soon as possible to reduce the complications of infection.
openaire   +2 more sources

Meningococcal and pneumococcal disease [PDF]

Paediatrics & Child Health, 2002
The licensure of new vaccines in 2001 in Canada means that pneumococcal and group C meningococcal infections can be added to the list of vaccine-preventable diseases. The successful control of these two diseases will require all provincial and territorial governments in Canada to add the new vaccines to their routine immunization programs ...
openaire   +2 more sources

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

mBio, 2018
Pediatric meningococcal sepsis often results in morbidity and/or death, especially in young children. Our understanding of the reasons why young children are more susceptible to both the meningococcal infection itself and a more fulminant course of the ...
Noortje de Haan, Navin P. Boeddha, Ebru Ekinci, Karli R. Reiding, Marieke Emonts, Jan A. Hazelzet, Manfred Wuhrer, Gertjan J. Driessen   +7 more
doaj   +1 more source

AMEND study protocol: a case–control study to assess the long-term impact of invasive meningococcal disease in Australian adolescents and young adults

BMJ Open, 2019
Introduction Invasive meningococcal disease (IMD) primarily causes disease in young children and adolescents and can cause long-term disability. Many countries are considering implementation of meningococcal B and/or meningococcal ACWY vaccines to ...
David Gordon, Helen Marshall, Mark McMillan, Peter Richmond, Christopher C Blyth, Jim Buttery, David Shaw, Belinda Barton, Bing Wang, Robert Booy, Hossein Afzali   +10 more
doaj   +1 more source

Societal costs due to meningococcal disease: a national registry-based study

ClinicoEconomics and Outcomes Research, 2018
Nina Gustafsson,1 Sandra Elkjær Stallknecht,1 Mette Skovdal,2 Peter Bo Poulsen,3 Lars Østergaard4 1Incentive, Holte, Denmark; 2Vaccines, Pfizer Denmark, Ballerup, Denmark; 3Health and Value, Pfizer Denmark, Ballerup, Denmark; 4Department of ...
Gustafsson N, Stallknecht SE, Skovdal M, Poulsen PB, Østergaard L   +4 more
doaj  

Meningococcal Disease

Journal of the Ceylon College of Physicians
Meningococcal disease, caused by Neisseria meningitidis, is a rapidly progressive, potentially life-threatening infection. The organism, an encapsu-lated Gram-negative diplococcus, is classified into at least 13 serogroups, with A, B, C, W, X, and Y being responsible for most invasive cases.
McNamara LA, Rubis AB.
europepmc   +3 more sources

Meningococcal disease. Polysaccharide meningococcal vaccines. The historical aspects and the current state of vaccine development. Report 2

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article describes clinical signs of meningococcal disease. It justifies the necessity of its vaccine prevention. The article provides with the historical data on the evolution of inoculants from corpuscular inactivated vaccines to modern ...
M. V. Abramtseva, A. P. Tarasov, T. I. Nemirovskaya   +2 more
doaj  

Atypical meningococcal meningitis with rashless presentation: A case report

Journal of Acute Disease, 2012
Meningococcal disease is the major health problem in developing world. The clinical presentation is varied, ranging from transient fever and bacteraemia to fulminant disease with death ensuing within hours of the onset of clinical symptoms. The classical
Sunita, Manpreet Singh, Dheeraj Kapoor
doaj   +1 more source