Results 81 to 90 of about 66,731 (293)

Development of a Recombinant Outer Membrane Vesicles (OMVs)‐Based Vaccine Against Helicobacter pylori Infection in Mice

Journal of Extracellular Vesicles, Volume 14, Issue 5, May 2025.
This study innovatively modified the structure of LPS for the recombinant H. pylori OMV vaccine, and utilised the vector advantage of OMVs to deliver the H. pylori main antigen proteins UreB, VacA and CagA to exert the synergistic effect of the vaccine, providing a new strategy for the design of H.
Qiong Liu, Biaoxian Li, Jinrong Ma, Xiao Lei, Junpeng Ma, Yanyan Da, Zhiyong Zhou, Jiaqi Tao, Xinyi Ren, Ting Zeng, Zhiting Xie, Haiyan Lin, Zihui Jin, Yi Wan, Liang Zhang, Donglin Lai, Yaping Guo, Jing Li, Yinpan Shang, Lu Shen, Ziwei Tao, Tian Gong, Chengsheng Zhang   +22 more
wiley   +1 more source

Epidemiologic Trends, Global Shifts in Meningococcal Vaccination Guidelines, and Data Supporting the Use of MenACWY-TT Vaccine: A Review

Infectious Diseases and Therapy, 2019
Neisseria meningitidis is a major cause of meningitis and septicemia with cases, outbreaks, and epidemics reported globally in industrialized and non-industrialized countries. N. meningitidis is categorized into 12 serogroups; however, only 5 serogroups (
Jessica Presa, Jamie Findlow, Jelena Vojicic, Scott Williams, Lidia Serra   +4 more
doaj   +1 more source

Mixture of Input-Output Hidden Markov Models for Heterogeneous Disease Progression Modeling [PDF]

arXiv, 2022
A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is unlikely for neurodegenerative disorders such as Parkinson's disease.
arxiv  

Childhood Vaccine Hesitancy as an Interaction‐Based Phenomenon

Sociology of Health &Illness, Volume 47, Issue 4, May 2025.
ABSTRACT The paper discusses the role of the interaction between parents and healthcare professionals in overcoming or heightening childhood vaccine hesitancy. Childhood vaccine hesitancy is seen as a set of attitudes and behaviours—that is, dispositions—that are highly dependent on how trust and vulnerability intersect during vaccination appointments.
Alice Scavarda, Mario Cardano, Luigi Gariglio   +2 more
wiley   +1 more source

Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]

, 2011
Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hibberd, Martin L, Kroll, J Simon, Langford, Paul R, Li, Ming-Shi, Wong, Hazel En En   +4 more
core   +1 more source

Meningococcal disease before and after the introduction of meningococcal serogroup C conjugate vaccine. Federal District, Brazil

Brazilian Journal of Infectious Diseases, 2014
Objectives: To analyze the behavior of meningococcal disease in the Federal District, Brazil, from 2005 to 2011, and to assess the direct impact of the meningococcal serogroup C conjugate vaccine.
Márcia de Cantuária Tauil, Cleidiane Santos Rodrigues de Carvalho, Ataiza César Vieira, Eliseu Alves Waldman   +3 more
doaj  

Statistics of infections with diversity in the pathogenicity [PDF]

arXiv, 2004
The statistics of outbreaks in a model for the propagation of meningococcal diseases is analyzed, taking into account the possibility that the population is fragmented into weakly connected patches. It is shown that, depending on the size of of the sample studied, the ratio between the variance and the mean of infected cases can vary from one (Poisson ...
arxiv  

An Economic Evaluation of Direct Oral Penicillin Challenge for De‐Labelling Low Risk Patients With a Penicillin Allergy Label

Clinical &Experimental Allergy, Volume 55, Issue 5, Page 378-390, May 2025.
The cost of the Direct Oral Penicillin Challenge (DPC) itself is only a fraction of the full costs required to test for a penicillin allergy label by non‐allergists. The costs of DPC varied between hospitals using a nurse‐led, pharmacist‐led, or mixture of pharmacists and nurses.
R. Bestwick, R. Bhogal, K. Kildonaviciute, B. Y. Ng, B. Jackson, C. Moriarty, C. Thomas, L. Savic, S. A. Misbah, M. T. Krishna, R. Mujica‐Mota   +10 more
wiley   +1 more source

Meningococcal disease serogroup C

Risk Management and Healthcare Policy, 2012
Félix O Dickinson1, Antonio E Pérez1, Iván E Cuevas21Department of Epidemiology, “Pedro Kourí” Institute, Havana, Cuba; 2Pharmacovigilance Group, Finlay Institute, Havana, CubaAbstract ...
Cuevas IE, Pérez AE, Dickinson FO   +2 more
doaj  

Patient follow‐up after discharge from the paediatric intensive care unit: A scoping review

Nursing in Critical Care, Volume 30, Issue 3, May 2025.
Abstract Background Most children admitted to a paediatric intensive care unit (PICU) now survive because of improvements in care. Many studies have identified the psychological, functional, cognitive and social impact of PICU admission on a child and their family. However, expert recommendations on follow‐up are lacking. Aim To identify the strategies
Delphine Micaëlli, Jérôme Naudin, Stéphane Dauger, Michaël Levy, Sébastien Kerever   +4 more
wiley   +1 more source