Results 41 to 50 of about 32,481 (179)

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., Balbao, J., Cabrera, O., Cuello, M., del Campo, J., Ferro, Valerie A., Gonzales, E., Romeu, B., Zayas, C.   +8 more
core  

Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]

, 2018
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert, Fenimore, Vincent L., Frew, Paula M., Goldbeck, Cameron, Himmelstein, Rebecca, Holloway, Ian W., Lutz, Chelsea S., Randall, Laura, Tan, Diane, Wu, Elizabeth   +9 more
core   +3 more sources

EPYSQLI (SB12; Biosimilar to Reference Eculizumab) in Asian and Non‐Asian Patients With Paroxysmal Nocturnal Hemoglobinuria: Subgroup Analysis of a Global Phase III Randomized Controlled Trial

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Introduction SB12 demonstrated equivalence to reference eculizumab (ECU) in complement inhibitor‐naïve patients with paroxysmal nocturnal hemoglobinuria (PNH) in the previous randomized, double‐blind, multi‐national, crossover, Phase III study.
Jun Ho Jang, Ciprian Tomuleasa, Hanna Oliynyk, Theerin Lanamtieng, Jihye Park, Younsoo Kim, Jinah Jung, Paola Russo, Soo Min Lim, Régis Peffaultde Latour   +9 more
wiley   +1 more source

Meningococcus this Winter : what was going on? [PDF]

, 1996
There was a time in the not very distant past when meningococcus was not being recognised locally. While laboratory sensitivity used to isolate Neisseria meningitidis has not changed in Malta, the frequency of its detection has increased, more so in the ...
Falzon, Dennis
core  

Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016 [PDF]

, 2019
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed.
Arghittu M., Barbui A. M., Bernaschi P., Bisbano A., Chironna M., Ciammaruconi A., De Nittis R., Fazio C., Galanti I. A., Giammanco A., Isola P., Mencacci A., Neri A., Pagani E., Stefanelli P., Vacca P., Vocale C.   +16 more
core   +1 more source

Position statement on the management of pregnancy in sickle cell disease

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 65, Issue 2, Page 183-189, April 2025.
Sickle cell disease (SCD) is a hereditary haemoglobinopathy which causes multi‐organ dysfunction. Pregnancies in SCD are high risk with significant maternal and fetal morbidity and mortality, including vaso‐occlusive crises, thrombosis, anaemia, placental insufficiency, fetal growth restriction, preterm birth and medication effects. High level evidence
Mimi Yue, Kylie Mason, Shelley Rowlands, Zane Kaplan, Debra Kennedy, Giselle Kidson‐Gerber   +5 more
wiley   +1 more source

Teenagers’ understandings of and attitudes towards vaccines and vaccine-preventable diseases: a qualitative study [PDF]

, 2013
<p>Background: To examine immunisation information needs of teenagers we explored understandings of vaccination and vaccine-preventable diseases, attitudes towards immunisation and experiences of immunisation.
Barbour, Bedford, Bloor, Bond, Brabin, Brownlie, Butler, Bynum, C. Patterson, Clark, Crocker, Duffell, E. Smith, Finn, Flynn, Gellin, Gordon, H. Bedford, Hilton, Hilton, Hilton, Hinds, Hobson-West, K. Hunt, Kale, Kitzinger, Lashkari, Maple, Marlow, Miller, Paranthaman, Pareek, Parrella, Peckham, Pelucchi, Pollard, Poltorak, Ramsay, Ritchie, S. Hilton, Slonim, Smailbegovic, Smith, Sporton, Streefland, Stretch, Woodhall, Yarwood, Zimet   +48 more
core   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of ALXN1820 (Tarperprumig) in Healthy Adults: Results of a Phase I Study

Clinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT Properdin is an endogenous positive regulator of the complement alternative pathway (AP). Tarperprumig (ALXN1820), a novel humanized bispecific antibody, binds properdin and albumin and is being developed to treat complement‐mediated diseases.
Avner Sandhu, Tong Shen, Paz Martin Herrero, Chao‐Xing Yuan, Samirah Qureshi, Xiaoyu Jiang, Ye Sheng, Christoph Gasteyger, Yang Dai   +8 more
wiley   +1 more source

Meningococcal antigen in diagnosis and treatment of group A meningococcal infections

The American Journal of Medicine, 1975
Meningococcal antigen was measured by countercurrent immunoelectrophoresis in the blood and cerebrospinal fluid of 200 patients with group A meningococcal meningitis. Antigen was detected in the blood of 27 (13.5 per cent) patients. These patients had a worse prognosis and a higher incidence of allergic complications, such as arthritis and vasculitis ...
Whittle, H, Greenwood, B, Davidson, N, Tomkins, A, Tugwell, P, Warrell, D, Zalin, A, Bryceson, A, Parry, E, Brueton, M, Duggan, M, Oomen, J, Rajkovic, A   +12 more
openaire   +3 more sources

Long‐Term Efficacy and Safety of Ravulizumab in Adults With Anti‐Acetylcholine Receptor Antibody‐Positive Generalized Myasthenia Gravis: Final Results From the Phase 3 CHAMPION MG Open‐Label Extension

European Journal of Neurology, Volume 32, Issue 4, April 2025.
Ravulizumab demonstrated clinically meaningful and durable efficacy and safety in adults with anti‐acetylcholine receptor antibody‐positive generalized myasthenia gravis in the CHAMPION MG open‐label extension (OLE) study. Improvements from baseline in MG‐ADL, QMG, and MG‐QOL15r total scores, and the NeuroQOL Fatigue subscale scores achieved in ...
Tuan H. Vu, Renato Mantegazza, Djillali Annane, Masahisa Katsuno, Andreas Meisel, Michael W. Nicolle, Vera Bril, Rasha Aguzzi, Glen Frick, James F. Howard Jr, the CHAMPION MG Study Group   +10 more
wiley   +1 more source