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Human genetics of meningococcal infections. [PDF]
Hum Genet, 2020 AbstractNeisseria meningitidisis a leading cause of bacterial septicaemia and meningitis worldwide. Meningococcal disease is rare but can be life threatening with a tendency to affect children. Many studies have investigated the role of human genetics in predisposition toN. meningitidisinfection. These have identified both rare single-gene mutations as
Hodeib S +3 more
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Complement and meningococcal infection. [PDF]
BMJ, 1976 Serum C3 levels were measured in 211 patients with meningococcal disease. Low levels were found in 13 patients with acute meningococcaemia, and complement activation may have contributed to the peripheral circulatory collapse that was responsible for nine deaths.
Brian Greenwood +2 more
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Primary Health Care, 2001 Meningococcal disease is an important medical emergency demanding early diagnosis and prompt treatment. This article provides an overview of meningococcal infection and discusses mode of transmission, risk factors, prevention of spread, vaccination and current recommendations for treatment.
George Kassianos
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Antibiotics for preventing meningococcal infections. [PDF]
Cochrane Database Syst Rev, 2013 Meningococcal disease is a contagious bacterial infection caused by Neisseria meningitidis (N. meningitidis). Household contacts have the highest risk of contracting the disease during the first week of a case being detected. Prophylaxis is considered for close contacts of people with a meningococcal infection and populations with known high carriage ...
Zalmanovici Trestioreanu A +4 more
europepmc +7 more sources
A systematic review to identify research gaps in studies modeling MenB vaccinations against Neisseria infections. [PDF]
PLoS ONEThe genus Neisseria includes two major human pathogens: N. meningitidis causing bacterial meningitis/septicemia and N. gonorrhoeae causing gonorrhoea.
Soeren Metelmann +10 more
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Insight into Prevention of Neisseria Gonorrhoeae: A Short Review
Vaccines, 2022 Neisseria gonorrhoeae (gonococcus) and Neisseria meningitidis (meningococcus) are important global pathogens which cause the sexually transmitted diseases gonorrhea and meningitis, respectively, as well as sepsis.
Vincenza La Fauci +3 more
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Pediatria Polska, 2022 Invasive meningococcal disease is a dangerous bacterial infection that often leads to death or permanent disability. Immunization is the best strategy to protect individuals against invasive infections caused by Neisseria meningitidis.
Ernest Kuchar +10 more
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Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effect
npj Vaccines, 2021 Infections with Neisseria meningitidis and Neisseria gonorrhoeae have different clinical manifestations, but the bacteria share up to 80–90% genome sequence identity.
Yara Ruiz García +9 more
doaj +1 more source
Treatment of meningococcal infection [PDF]
Archives of Disease in Childhood, 2003 Aggressive early treatment of meningococcal disease can reduce mortality. This relies on prompt recognition and treatment of the complications of septicaemia and meningitis, appropriate ongoing intensive care where necessary, and adequate management of multiple organ failure.
S B Welch, S Nadel
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Microorganisms, 2020 The description of invasive meningococcal disease that is provoked by Neisseria meningitidis (Nm) is frequently restricted to meningitis. However, a wide panel of clinical presentations can be encountered including severe forms with intense inflammatory ...
Michael Levy +2 more
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