Results 11 to 20 of about 22,716 (254)

Hydrocephalus and Cerebral Small Vessel Disease in an Adult With Meningococcal Meningitis and Dilated Cardiomyopathy: A Fatal Outcome. [PDF]

Clin Case Rep
ABSTRACT Meningococcal meningitis can lead to serious neurological complications such as hydrocephalus directly and contribute to cerebral small vessel disease indirectly, especially in patients with pre‐existing conditions like dilated cardiomyopathy.
Mohamed Y, Mohamed A, Elemam A, Babiker A.   +3 more
europepmc   +2 more sources

Two New Kindreds with Complete Factor D Deficiency. [PDF]

Eur J Immunol
The complement system plays a crucial role in immune defense, and factor D deficiency is a rare immunodeficiency associated with life‐threatening bacterial infections. We report two new cases of complete factor D deficiency, including the first described in a Down syndrome patient, highlighting the need to investigate complement deficiencies in ...
Puel M, Rwayane K, Vieira Martins P, Chbihi M, Rieux-Laucat F, Rosain J, Jeziorski E, Boisson B, Casanova JL, Frémeaux-Bacchi V, El Sissy C.   +10 more
europepmc   +2 more sources

Cortactin: A universal host cytoskeletal target of Gram‐negative and Gram‐positive bacterial pathogens

Molecular Microbiology, Volume 118, Issue 6, Page 623-636, December 2022., 2022
In host‐pathogen interactions, actin‐cytoskeletal dynamics play a crucial role in successful adherence, invasion, and intracellular motility by many intruding microbes. To achieve this goal, bacterial pathogens target major host regulators, one of which is the key actin‐binding protein and class‐II actin nucleation‐promoting factor cortactin.
Irshad Sharafutdinov, Jakob Knorr, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer   +4 more
wiley   +1 more source

Exploring the Ability of Meningococcal Vaccines to Elicit Mucosal Immunity: Insights from Humans and Mice

Pathogens, 2021
Neisseria meningitidis causes a devastating invasive disease but is also a normal colonizer of the human nasopharynx. Due to the rapid progression of disease, the best tool to protect individuals against meningococcal infections is immunization. Clinical
Elissa G. Currie, Scott D. Gray-Owen
doaj   +1 more source

Transmissibility and pathogenicity of the emerging meningococcal serogroup W sequence type-11 complex South American strain: a mathematical modeling study

BMC Medicine, 2020
Background The recent emergence of strains belonging to the meningococcal serogroup W (MenW) sequence type-11 clonal complex and descending from the South American sub-lineage (MenW:cc11/SA) has caused significant shifts in the epidemiology of ...
Matthieu Domenech de Cellès, Helen Campbell, Ray Borrow, Muhamed-Kheir Taha, Lulla Opatowski   +4 more
doaj   +1 more source

A Double Whammy Pneumonia: The First Reported Case of Concurrent and SARS-CoV-2 Pneumonia

Journal of Investigative Medicine High Impact Case Reports, 2022
Meningococcal pneumonia (MP) is a rare manifestation of meningococcal disease. The MP was first described in 1907 when Neisseria meningitidis (NM) isolates were identified in sputum samples obtained from soldiers with pneumonia.
Michael Valdez MD, Rupam Sharma MD, Jaspreet Joshi MS4, Harleen Sandhu MD, Shikha Mishra MD, Rasha Kuran MD, Arash Heidari MD   +6 more
doaj   +1 more source

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

mBio, 2018
Pediatric meningococcal sepsis often results in morbidity and/or death, especially in young children. Our understanding of the reasons why young children are more susceptible to both the meningococcal infection itself and a more fulminant course of the ...
Noortje de Haan, Navin P. Boeddha, Ebru Ekinci, Karli R. Reiding, Marieke Emonts, Jan A. Hazelzet, Manfred Wuhrer, Gertjan J. Driessen   +7 more
doaj   +1 more source

A Comprehensive Review of Meningococcal Disease Burden in India

Infectious Diseases and Therapy, 2020
Introduction Meningococcal disease caused by Neisseria meningitidis has a high case fatality rate. Of 12 distinct serogroups, A, B, C, W-135 (W) and Y cause the majority of infections.
Ashok Kumar Dutta, Subramanian Swaminathan, Veronique Abitbol, Shafi Kolhapure, Sripriya Sathyanarayanan   +4 more
doaj   +1 more source

Spatio-Temporal Analysis of Epidemic Phenomena Using the R Package surveillance [PDF]

Journal of Statistical Software (2017); 77 (11): 1-55, 2014
The availability of geocoded health data and the inherent temporal structure of communicable diseases have led to an increased interest in statistical models and software for spatio-temporal data with epidemic features. The open source R package surveillance can handle various levels of aggregation at which infective events have been recorded ...
arxiv   +1 more source

Neisseria Meningitidis Urethritis in a Thai Male

Journal of Health Science and Medical Research (JHSMR), 2021
Although Neisseria meningitidis (N. meningitidis) urogenital infections have been reported widely, meningococcal urethritis has not been reported previously in Thailand.
Jaray Tongtoyai, Nongkran Tatakham, Thitima Cherdtrakulkiat, Pachara Sirivongrangson, Andrew Hickey   +4 more
doaj   +1 more source