Results 51 to 60 of about 22,818 (176)

Clinically Suspected Invasive Meningococcal Disease Presenting With Purpura Fulminans‐Like Rash, Septic Shock, Multiorgan Dysfunction, and Recovery From ARDS in a Previously Healthy Child

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Clinically suspected invasive meningococcal disease can deteriorate rapidly in previously well children. Prompt recognition of the petechial–purpuric rash with shock, early empirical antibiotics, and aggressive supportive pediatric intensive care are cornerstones of management as multiorgan dysfunction and Acute Respiratory Distress Syndrome ...
Shatha Omar, Adil Alsweis, Amr Khaled, Noor Nabresi, Mosub Qatu, Yahya Qahwash, Mahfouth Jallad   +6 more
wiley   +1 more source

The Meningococcal Cysteine Transport System Plays a Crucial Role in Neisseria meningitidis Survival in Human Brain Microvascular Endothelial Cells

mBio, 2018
While Neisseria meningitidis typically exists in an asymptomatic nasopharyngeal carriage state, it may cause potentially lethal diseases in humans, such as septicemia or meningitis, by invading deeper sites in the body. Since the nutrient compositions of
Hideyuki Takahashi, Haruo Watanabe, Kwang Sik Kim, Shigeyuki Yokoyama, Tatsuo Yanagisawa   +4 more
doaj   +1 more source

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni, Ebba Qviberg, Edward Chaloner, Hayley Lavender, Maisem Laabei   +4 more
wiley   +1 more source

Complement Factor H‐Based Therapeutics: A Comprehensive Overview

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers, Emmy J. Buter, Richard B. Pouw   +2 more
wiley   +1 more source

2024 update on meningococcal vaccination recommendations for children and adults

Pediatria Polska
The best protection against invasive infections caused by meningococcus (Neisseria meningitidis), which can lead to death or permanent disability, is immunization.
Ernest Kuchar, Hanna Czajka, Ewelina Gowin, Maria Katarzyna Borszewska-Kornacka, Aneta Nitsch-Osuch, Anna Skoczyńska, Leszek Szenborn, August Wrotek, Jacek Wysocki, Agnieszka Mastalerz-Migas, Jarosław Peregud-Pogorzelski, Teresa Jackowska   +11 more
doaj   +1 more source

Meningococcal Infection

Russian Pediatric Journal, 2023
.
openaire   +1 more source

Overwhelming Post‐Splenectomy Sepsis From Capnocytophaga canimorsus

International Journal of Laboratory Hematology, EarlyView.
Maitlyn Hsia, Maud Ahmad, Cyrus C. Hsia, Benjamin Chin‐Yee   +3 more
wiley   +1 more source

Meningococcal vaccination counts and public attention: A time-series study from Türkiye

Human Vaccines & Immunotherapeutics
Meningococcal infections remain a significant cause of morbidity and mortality in childhood. In Türkiye, meningococcal vaccines are not included in the national immunization program and are mainly administered through optional, self-funded services. This
Aysun Boğa, Ezgi Nafile Sayman, Nicel Yıldız Silahlı, Timucin Imdadoglu, Elif Serap Esen, Sirin Guven, Ener Çağrı Dinleyici   +6 more
doaj   +1 more source

IMPACT OF MENINGOCOCCAL C VACCINATION ON HOSPITALIZATIONS AND DEATHS FROM MENINGOCOCCAL INFECTION IN BRAZIL (2000–2022)

Brazilian Journal of Infectious Diseases
Introduction/Objective: Meningococcal infections (MI), caused by Neisseria meningitidis, are severe and potentially lethal. Introduction of the meningococcal C vaccine into the Programa Nacional de Imunizações (PNI) in 2010 sought to reduce these ...
Camila Luana Zaleski, Ana dos Santos Alves Camargo, Maria Eduarda da Silva Ruela, Anna Thereza Rocha Pereira, Bruna Moreira Martins Pacheco, Isabela Bettu Bini, Laura Freitas Rocha, Victória Heloísa Mazei Costa, Amanda Mayhuma Alves Ferreira, Marcus Aurélio de Oliveira Junior   +9 more
doaj   +3 more sources

Invasive meningococcal disease

Arquivos de Neuro-Psiquiatria, 2013
Invasive meningococcal disease (IMD) is a major public health and continues to cause substantial mortality and morbidity. Serotype C is the most frequent in Brazil.
Vanessa L. Strelow, Jose E. Vidal
doaj   +1 more source