Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Booth, C. +9 more
core
Risk of transmitting meningococcal infection by transient contact on aircraft and other transport. [PDF]
Contact tracing of persons with meningococcal disease who have travelled on aeroplane or other multi-passenger transport is not consistent between countries.
Hellenbrand, W +4 more
core +3 more sources
Serogroup W-135 Meningococcal Disease during the Hajj, 2000
An outbreak of serogroup W-135 meningococcal disease occurred during the 2000 Hajj in Saudi Arabia. Disease was reported worldwide in Hajj pilgrims and their close contacts; however, most cases were identified in Saudi Arabia.
Jairam R. Lingappa +14 more
doaj +1 more source
Invasive meningococcal disease (IMD) is rare but associated with high morbidity and mortality. In the United States, the most vulnerable age groups are infants and adolescents/young adults, and the most common type of IMD is caused by serogroup B (MenB).
Jessica Presa +4 more
doaj +1 more source
Immunization strategies targeting newly arrived migrants in Non-EU countries of the mediterranean basin and black sea [PDF]
Background: The World Health Organization recommends that host countries ensure appropriate vaccinations to refugees, asylum seekers and migrants. However, information on vaccination strategies targeting migrants in host countries is limited. Methods: In
Declich, Silvia +7 more
core +1 more source
ABSTRACT Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life‐threatening disorder characterized by complement‐mediated hemolysis. Crovalimab, a novel anti‐C5 monoclonal antibody, may offer a more convenient alternative to current therapies, highlighting the need for a comprehensive analysis of its efficacy and safety.
Hammad Javaid +11 more
wiley +1 more source
The human host defense peptide LL-37 interacts with Neisseria meningitidis capsular polysaccharides and inhibits inflammatory mediators release. [PDF]
Capsular polysaccharides (CPS) are a major virulence factor in meningococcal infections and form the basis for serogroup designation and protective vaccines.
Susu M Zughaier +4 more
doaj +1 more source
Safety and efficacy of eculizumab in adult and pediatric patients with aHUS, with or without baseline dialysis [PDF]
C
Hourmant, Maryvonne +5 more
core +1 more source
Direct Switch From Iptacopan to Pegcetacoplan in a Patient With Paroxysmal Nocturnal Hemoglobinuria
ABSTRACT Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal hematologic disorder treated with complement inhibitors. Currently, patients with suboptimal response to C5 inhibitors may be switched to proximal complement inhibitors, such as pegcetacoplan, danicopan, or iptacopan.
Vitalii Latyshev +3 more
wiley +1 more source
Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries.
Claudia Ferreira de Andrade +3 more
doaj +1 more source

