From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
C5‐inhibition may represent an effective adjunctive treatment in therapy‐refractory myasthenic crisis, including thymoma‐associated MG (TAMG). ABSTRACT Introduction Generalized myasthenia gravis (gMG) may progress to life‐threatening myasthenic crises (MC) requiring mechanical ventilation.
Lea Gerischer +24 more
wiley +1 more source
2024 update on meningococcal vaccination recommendations for children and adults
The best protection against invasive infections caused by meningococcus (Neisseria meningitidis), which can lead to death or permanent disability, is immunization.
Ernest Kuchar +11 more
doaj +1 more source
Invasive meningococcal disease
Invasive meningococcal disease (IMD) is a major public health and continues to cause substantial mortality and morbidity. Serotype C is the most frequent in Brazil.
Vanessa L. Strelow, Jose E. Vidal
doaj +1 more source
Effectiveness of antibiotics given before admission in reducing mortality from meningococcal disease: systematic review. [PDF]
OBJECTIVE: To review the evidence for effectiveness of treatment with antibiotics before admission in reducing case fatality from meningococcal disease. DESIGN: Systematic review. DATA SOURCES: Cochrane register of trials and systematic reviews, database
Hahné, Susan J M +8 more
core +1 more source
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson +5 more
wiley +1 more source
Introduction/Objective: Meningococcal infections (MI), caused by Neisseria meningitidis, are severe and potentially lethal. Introduction of the meningococcal C vaccine into the Programa Nacional de Imunizações (PNI) in 2010 sought to reduce these ...
Camila Luana Zaleski +9 more
doaj +3 more sources
Invasive meningococcal disease in three siblings with hereditary deficiency of the 8th component of complement: Evidence for the importance of an early diagnosis [PDF]
Deficiency of the eighth component of complement (C8) is a very rare primary immunodeficiency, associated with invasive, recurrent infections mainly caused by Neisseria species.
A Orren +27 more
core +1 more source
Antibiotics for eradicating meningococcal carriages: Network meta-analysis and investigation of evidence inconsistency [PDF]
AIM: To compare different antibiotics for eradicating the carriage of Neisseria meningitidis, and to investigate heterogeneity and evidence inconsistency.
Abdelhamid, Asmaa +3 more
core +1 more source
Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo +8 more
doaj +1 more source

