Results 81 to 90 of about 38,002 (265)

Tocilizumab provides a potential therapeutic option for the management of hyperhaemolysis syndrome in sickle cell disease: A case series and brief narrative overview of the literature

Transfusion Medicine, Volume 36, Issue 1, Page 66-71, February 2026.
Abstract Background and Objectives Hyperhaemolysis syndrome is a life‐threatening complication of transfusion, potentially triggered by macrophage activation, with limited treatment options. Tocilizumab, an anti‐IL6 monoclonal antibody, has mechanistic rationale for use and has been shown to be effective in a small number of cases.
S. Wolf, B. Singh, A. Zaidi, P. Greaves, F. Oyesanya, S. Bennett, B. Kaya, F. Barroso, P. Telfer   +8 more
wiley   +1 more source

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

, 2009
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A, Dockerty, John D, Herbison, Peter, Hill, Philip C, Howie, Stephen RC, Jasseh, Momodou, Jeffries, David J, Mulholland, Kim, Rutherford, Merrin E   +8 more
core   +1 more source

Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]

, 2012
WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black, Catto, Choudhuri, George, Graham, Higginson, Horwood, Huda, Lawn, Nair, Nair, Nair, O'Brien, Osterholt, Rudan, Rudan, Rudan, Rudan, Rudan, Tomlinson, Watt, Webster   +21 more
core   +3 more sources

Laparoscopic Partial Splenectomy for a Giant Congenital Splenic Cyst in a Child: Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT An 11‐year‐old boy with a 16 × 14.5 cm congenital splenic cyst underwent laparoscopic upper‐pole partial splenectomy after negative hydatid workup and vaccination. Recovery was uneventful; histology confirmed epithelial cyst. Spleen‐preserving surgery provided durable symptom relief and preserved function.
Ahmed Alanzi, Dawood Alatefi, Malik Alkabazi, Bano Alsaleh, Khaled M. AlAani, Samah Hakmi   +5 more
wiley   +1 more source

Invasive meningococcal disease

Arquivos de Neuro-Psiquiatria, 2013
Invasive meningococcal disease (IMD) is a major public health and continues to cause substantial mortality and morbidity. Serotype C is the most frequent in Brazil.
Vanessa L. Strelow, Jose E. Vidal
doaj   +1 more source

Autosplenectomy in a Patient With Autoimmune Polyglandular Syndrome Type 2 (APS‐2)

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Autoimmune glandular syndrome type 2 is a complex genetic condition where a triad of endocrinopathies is involved, namely, Addison’s disease, type 1 diabetes, and/or autoimmune thyroid disorder. The disease predisposes one to a variety of other autoimmune associations.
Luqman S. Fauzi, Airin Jyoty, Yashwin Sredharan, Manohara Kenchaiah, Osamu Isozaki   +4 more
wiley   +1 more source

What is the evidence for giving chemoprophylaxis to children or students attending the same preschool, school or college as a case of meningococcal disease? [PDF]

, 2011
We performed a systematic literature review to assess the effectiveness of chemoprophylaxis for contacts of sporadic cases of invasive meningococcal disease (IMD) in educational settings.
Ackerman, Barker, Bernabeu, Cartwright, Davison, Dawson, Favorova, Ferson, Fraser, G. HANQUET, Giovanetti, González de Aledo, Granerod, Hastings, Hoek, J. M. STUART, Jacobson, Juels, Norton, O'Donovan, P. STEFANOFF, Palau, Riordan, Robinson, S. HEUBERGER, S. NIELSEN, Scholten, Schubiger, Stefanoff, Sutton, W. HELLENBRAND   +30 more
core   +2 more sources

Evaluating the Real‐World Safety of Ravulizumab in Generalized Myasthenia Gravis: Insights From a Detailed Analysis of FAERS Data

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Ravulizumab represents the inaugural long‐acting complement C5 inhibitor that has received approval in various countries around the globe for individuals diagnosed with generalized myasthenia gravis (gMG) who are positive for anti‐acetylcholine receptor antibodies.
Yakun Wang, Qian Guo, Jiayu Bai, Jiaqi Shi, Ziquan Yang, Hongda Liu   +5 more
wiley   +1 more source

Differential expression of proinflammatory cytokines and their inhibitors during the course of meningococcal infections [PDF]

, 1994
Contains fulltext : 4764.pdf (publisher's version ) (Open ...
Bartelink, A.K.M., Dalen, R. van, Demacker, P.N.M., Deuren, M. van, Gallati, H., Meer, J.W.M. van der, Nice, J.L. van, Sauerwein, R.W., Ven-Jongekrijg, J. van der   +8 more
core   +1 more source

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong, Na Li, Ziheng Li, He Wang, Di Zhang, Hong Chu, Zhichao Lu, Aiqing Jia, Fengyang Li, Liancheng Lei, Zhong Peng   +10 more
wiley   +1 more source