Results 81 to 90 of about 22,716 (254)

Meningococcal disease in adolescents and young adults: a review of the rationale for prevention through vaccination

Human Vaccines & Immunotherapeutics, 2019
Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is characterized by high mortality and morbidity. While IMD incidence peaks in both infants and adolescents/young adults, carriage rates are often highest in the latter age groups ...
Cynthia Burman, Lidia Serra, Charles Nuttens, Jessica Presa, Paul Balmer, Laura York   +5 more
doaj   +1 more source

Results From a Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ANX005, a C1q Inhibitor, in Patients With Guillain–Barré Syndrome

Journal of the Peripheral Nervous System, Volume 30, Issue 1, March 2025.
ABSTRACT Background and Aims Guillain–Barré syndrome (GBS) is an acute autoimmune peripheral neuropathy driven by autoantibodies and classical complement pathway activation. Despite treatments with intravenous immunoglobulin or plasma exchange, GBS remains characterized by variability in recovery and high incidence of residual disabilities.
Quazi Deen Mohammad, Zhahirul Islam, Nowshin Papri, Shoma Hayat, Israt Jahan, Khan Abul Kalam Azad, Dean R. Artis, Benjamin Hoehn, Eric Humphriss, Ping Lin, Ted Yednock, Henk‐André Kroon   +11 more
wiley   +1 more source

A Case of Atypical Hemolytic Uremic Syndrome With a Complement Factor I Mutation Triggered by a Femoral Neck Fracture

Nephrology, Volume 30, Issue 3, March 2025.
ABSTRACT Atypical hemolytic uremic syndrome is a thrombotic microangiopathy caused by the abnormal activation of the alternative complement pathway. Mutations in complement‐related genes and autoantibodies against complement regulators are involved in the pathogenesis of this condition; the frequency of, and prognosis of patients harbouring, each ...
Toshiki Kano, Hiroaki Io, Yu Sasaki, Masahiro Muto, Sayaka Muto, Kei Ogiwara, Arisa Ikeda, Hiroyuki Iwasaki, Yusuke Suzuki   +8 more
wiley   +1 more source

Meningococcal vaccination in pregnancy

Human Vaccines & Immunotherapeutics, 2018
Invasive meningococcal disease causes meningitis and septicemia worldwide with highest rates of disease occurring in children
Bahaa Abu Raya, Manish Sadarangani
doaj   +1 more source

Invasive Meningococcal Disease, Utah, 1995–2005

Emerging Infectious Diseases, 2007
Trends in invasive meningococcal disease in Utah during 1995–2005 have differed substantially from US trends in incidence rate and serogroup and age distributions.
Rachelle B. Boulton, Stephen C. Alder, Susan Mottice, A. Peter Catinella, Carrie L. Byington   +4 more
doaj   +1 more source

Numerical considerations about the SIR epidemic model with infection age [PDF]

arXiv, 2020
We analyse the infection-age-dependent SIR model from a numerical point of view. First, we present an algorithm for calculating the solution the infection-age-structured SIR model without demography of the background host. Second, we examine how and under which conditions, the conventional SIR model (without infection-age) serves as a practical ...
arxiv  

A case of invasive meningococcal disease presenting as myopericarditis

Clinical Infection in Practice, 2021
Background: Neisseria meningitidis is a universally-feared Gram negative diplococcus, and infection confers high rates of morbidity and mortality despite effective antimicrobial therapy.
Simon M. Durkin, Clemency Britton, Graham S. Cooke, Ravi Mehta   +3 more
doaj  

Serosubtipos de meningococo B causantes de enfermedad invasiva en Cantabria y concordancia con la cepa de la vacuna cubana Meningococcus B serosubtypes causing invasive disease in Cantabria [Spain] and agreement with the Cuban vaccine strain

Gaceta Sanitaria, 2004
Objetivo: Conocer los serosubtipos de meningococo B causantes de enfermedad invasiva en Cantabria y el porcentaje de concordancia con la cepa de la vacuna cubana VA-Mengoc-BC.
Álvaro González de Aledo, Luis Viloria
doaj  

Evaluation of pharyngeal carriage of Neisseria meningitidis in Tehran, Iran

New Microbes and New Infections, 2022
Meningitis and meningococcal septicemia are potentially life-threatening illnesses; young people in educational institutions have been repeatedly exposed to outbreaks of meningococcal infections.
A. Fahimzad, M. Khatmi, F. Shiva, S.E. Mortazavi, F. Shirvani, F.A. Gorji   +5 more
doaj  

SIS Epidemic Spreading with Heterogeneous Infection Rates [PDF]

arXiv, 2015
In this work, we aim to understand the influence of the heterogeneity of infection rates on the Susceptible-Infected-Susceptible (SIS) epidemic spreading. Employing the classic SIS model as the benchmark, we study the influence of the independently identically distributed infection rates on the average fraction of infected nodes in the metastable state.
arxiv