Background and Objectives: Toll-like receptor (TLR2) gene plays an important role in the pathogenesis of bacterial meningitis (such as meningococcal meningitis and pneumococcal meningitis).
Praveen Kumar Chandra Sekar +1 more
doaj +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
A Seroepidemiological Study of Serogroup A Meningococcal Infection in the African Meningitis Belt.
The pattern of epidemic meningococcal disease in the African meningitis belt may be influenced by the background level of population immunity but this has been measured infrequently.
Olivier Manigart +33 more
doaj +1 more source
Assessment of acute headache in adults - what the general physician needs to know. [PDF]
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal +9 more
core +1 more source
Detection of the United States Neisseria meningitidis urethritis clade in the United Kingdom, August and December 2019 - emergence of multiple antibiotic resistance calls for vigilance. [PDF]
Since 2015 in the United States (US), the US Neisseria meningitidis urethritis clade (US_NmUC) has caused a large multistate outbreak of urethritis among heterosexual males.
Borrow, R +12 more
core +2 more sources
Background During fulminant meningococcal septicaemia, meningococci are often observed in the cerebrospinal fluid (CSF) although the patients have frequently no meningeal symptoms.
Mehdi Hage-Sleiman +8 more
doaj +1 more source
Māori and community news constructions of Meningococcal B: the promotion of a moral obligation to vaccinate [PDF]
News media communicate various risks of disease, showcase medical breakthroughs and disseminate texts that both reflect and renegotiate shared cultural understandings of health and illness. Little is known about the role of Māori and community news media
Chamberlain, Kerry +5 more
core +2 more sources
Vaccine prevention of meningococcal disease in Africa: Major advances, remaining challenges
Africa historically has had the highest incidence of meningococcal disease with high endemic rates and periodic epidemics. The meningitis belt, a region of sub-Saharan Africa extending from Senegal to Ethiopia, has experienced large, devastating ...
Mustapha M. Mustapha, Lee H. Harrison
doaj +1 more source
BackgroundBacterial meningitis is associated with significant burden in Brazil. In 2010, both 10-valent pneumococcal conjugate vaccine and meningococcal capsular group C conjugate vaccine were introduced into the routine vaccination schedule. Haemophilus
Luciano Cesar Pontes Azevedo +2 more
doaj +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source

