Results 81 to 90 of about 30,317 (268)

Hydrocephalus and Cerebral Small Vessel Disease in an Adult With Meningococcal Meningitis and Dilated Cardiomyopathy: A Fatal Outcome

Clinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Meningococcal meningitis can lead to serious neurological complications such as hydrocephalus directly and contribute to cerebral small vessel disease indirectly, especially in patients with pre‐existing conditions like dilated cardiomyopathy.
Yousif Mohamed, Ahmed Mohamed, Abubaker Elemam, Abubaker Babiker   +3 more
wiley   +1 more source

Meningococcal vaccines in Canada: An update [PDF]

Paediatrics & Child Health, 2011
Meningococcal infection is serious, often resulting in fulminant sepsis or meningitis. There are two main types of meningococcal conjugate vaccine currently available in Canada: serotype C meningococcal conjugate, and quadrivalent conjugate for serotypes A, C, Y, and W-135. The immunological characteristics that inform ongoing immunization policies, as
MI Salvadori, R Bortolussi
openaire   +3 more sources

Homology modelling of transferrin-binding protein A from Neisseria meningitidis [PDF]

, 2005
Neisseria meningitidis, a causative agent of bacterial meningitis, obtains transferrin-bound iron by expressing two outer membrane located transferrin-binding proteins, TbpA and TbpB.
Evans, RW, Gorringe, AR, Oakhill, JS, Sutton, BJ   +3 more
core   +2 more sources

Position statement on the management of pregnancy in sickle cell disease

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 65, Issue 2, Page 183-189, April 2025.
Sickle cell disease (SCD) is a hereditary haemoglobinopathy which causes multi‐organ dysfunction. Pregnancies in SCD are high risk with significant maternal and fetal morbidity and mortality, including vaso‐occlusive crises, thrombosis, anaemia, placental insufficiency, fetal growth restriction, preterm birth and medication effects. High level evidence
Mimi Yue, Kylie Mason, Shelley Rowlands, Zane Kaplan, Debra Kennedy, Giselle Kidson‐Gerber   +5 more
wiley   +1 more source

Trends and variations in the epidemiology of meningococcal disease in Kuwait 1987–2013

Journal of Infection and Public Health, 2015
Summary: The introduction of Haemophilus influenzae type b (Hib) conjugate vaccine and conjugate pneumococcal vaccine into routine childhood vaccination in Kuwait has resulted in the emergence of Neisseria meningitidis as the leading cause of invasive ...
Entesar H. Husain, Mohammad Barakat, Mosaab Al-Saleh   +2 more
doaj  

Safety and Immunogenicity of a Tetravalent Polysaccharide Vaccine Against Meningococcal Disease

Journal of the Formosan Medical Association, 2009
Meningococcal disease, including meningitis and sepsis, usually follows an invasive infection by Neisseria meningitidis, and is a major cause of death and morbidity worldwide.
Pei-Lan Shao, Luan-Yin Chang, Szu-Min Hsieh, Shan-Chwen Chang, Sung-Ching Pan, Chun-Yi Lu, Yu-Chia Hsieh, Chin-Yun Lee, Kurt Dobbelaere, Dominique Boutriau, Haiwen Tang, Hans L. Bock, Li-Min Huang   +12 more
doaj   +1 more source

Immunogenicity and safety of a quadrivalent meningococcal tetanus toxoid-conjugate vaccine (MenACYW-TT) in healthy toddlers: a Phase II randomized study

Human Vaccines & Immunotherapeutics, 2020
Neisseria meningitidis can lead to invasive meningococcal disease to which young children are particularly vulnerable. We assessed the immunogenicity and safety of Sanofi Pasteur’s investigational quadrivalent (serogroups A, C, Y, and W) meningococcal ...
Timo Vesikari, Ray Borrow, Aino Forsten, Helen Findlow, Mandeep S. Dhingra, Emilia Jordanov   +5 more
doaj   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of ALXN1820 (Tarperprumig) in Healthy Adults: Results of a Phase I Study

Clinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT Properdin is an endogenous positive regulator of the complement alternative pathway (AP). Tarperprumig (ALXN1820), a novel humanized bispecific antibody, binds properdin and albumin and is being developed to treat complement‐mediated diseases.
Avner Sandhu, Tong Shen, Paz Martin Herrero, Chao‐Xing Yuan, Samirah Qureshi, Xiaoyu Jiang, Ye Sheng, Christoph Gasteyger, Yang Dai   +8 more
wiley   +1 more source

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., Balbao, J., Cabrera, O., Cuello, M., del Campo, J., Ferro, Valerie A., Gonzales, E., Romeu, B., Zayas, C.   +8 more
core  

Immunogenicity and safety of meningococcal vaccines, MenACWY-CRM and 4CMenB, in groups at increased risk for meningococcal disease

Expert Review of Vaccines
Introduction Individuals with immunocompromising conditions (e.g. asplenia, complement deficiency, HIV infection) or with high exposure to Neisseria meningitidis (e.g.
Shravani Bobde, Chiranjiwi Bhusal, Catherine A. Cosgrove, Woo-Yun Sohn   +3 more
doaj   +1 more source