Results 131 to 140 of about 5,179 (252)

A Narrow Medial Femoral Condyle Width Is Associated With Anteromedial Rotatory Instability After Anterior Cruciate Ligament Injury

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To identify bone morphological risk factors and injury patterns of medial structural injuries in patients with anteromedial rotatory instability (AMRI) after anterior cruciate ligament (ACL) injury. Methods This comparative study analyzed patients’ data between August 2024 and June 2025.
Shengkun Wu, Ruoxi Zhang, Yu Liu, Yi Zheng, Zhikuan Li, Jiangtao Dong   +5 more
wiley   +1 more source

Morphological, morphometrical and histological characteristics of Menisci in domestic cats (Felis catus) [PDF]

This study aimed to investigate the morphological and morphometric features, as well as the histological composition of the medial and lateral menisci of domestic cats. A total of 180 menisci were obtained from 45 skeletally mature cat cadavers, followed
Noor, Mohd Akmal Mohd, Zabiddin, Nur Izzati Inani, Ghazali, Mohd Faizal, Ariffin, Siti Mariam Zainal, Chai, Min Hian, Azman, Dhiya Athirah, Bakar, Md Zuki Abu   +6 more
core   +1 more source

Indices of Systemic Inflammation Are Elevated in Women With Evidence of Metabolic Syndrome After Anterior Cruciate Ligament Reconstruction

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To investigate the association between metabolic syndrome (MetSy) and systemic indices of the immune system and inflammation after anterior cruciate ligament reconstruction (ACLR). Methods This retrospective study included adult patients (≥18 years) who underwent ACLR at a single academic institution between 2009 and 2022.
Marina Abdelshahid, Sonu Bae, Hayden Price, Hawraa Al Janabi, Catherine Rock, Anthony Mantor, Nicholas Apseloff, Christopher C. Kaeding, Robert A. Magnussen, David C. Flanigan, Tyler Barker   +10 more
wiley   +1 more source

The effect of mechanical stress on the stiffness of articular cartilage and its role in the aetiology of osteoarthrosis [PDF]

, 1988
Although a substantial amount is known about the pathogenesis of osteoarthrosis, its aetiology and in particular the role that mechanical factors play, remains unclear.
Swann, Anthony Charles
core  

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Study on the correlation between shear wave elastography and MRI grading of meniscal degeneration

Journal of Orthopaedic Surgery and Research
Background Shear Wave Elastography (SWE) offers quantitative insights into the hardness and elasticity characteristics of tissues. The objective of this study is to investigate the correlation between SWE of the menisci and MRI-assessed degenerative ...
Ran Ye, Hua-Hua Xiong, Xiao Liu, Jun-Xing Yang, Jian-Dong Guo, Jian-Wen Qiu   +5 more
doaj   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

Allotransplantation of frozen irradiated menisci in rabbits

, 1992
The meniscus is essential for normal knee function. Previously considered unimportant, removal was performed when injured. This frequently led to degenerative arthritic changes.
Rubins, Ian Michael
core  

MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice

Arthritis &Rheumatology, Accepted Article.
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source