Results 71 to 80 of about 5,179 (252)

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

open access: yesAdvanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu   +7 more
wiley   +1 more source

Biomechanical comparison of menisci from different species and artificial constructs [PDF]

open access: yes, 2013
Background: Loss of meniscal tissue is correlated with early osteoarthritis but few data exist regarding detailed biomechanical properties (e. g. viscoelastic behavior) of menisci in different species commonly used as animal models.
Andreas Buettner   +19 more
core   +3 more sources

Discoid lateral meniscus and its arthroscopic treatment

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated the results of arthroscopic meniscectomy in patients with lateral discoid menisci of the knee.\nMethods: Lateral discoid menisci were documented in 274 patients, of whom 183 patients (110 males, 73 females; mean age 34.8 years ...
Mehmet Asik   +5 more
doaj  

Regional and zonal histo-morphological characteristics of the lapine menisci

open access: yes, 2010
The menisci have crucial weight-bearing roles in the knee. Regional variations in structure and cellularity of the meniscus have only been minimally investigated. Therefore, the goal of this study was to illustrate the regional cell density, tissue area,
Nicole M. Lepinski   +7 more
core   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Upper and lower tear menisci on contact lenses

open access: yes, 2009
The purpose of this study was to measure upper and lower tear menisci on contact lenses using real time optical coherence tomography (OCT). Both eyes of 20 adapted contact lens wearers were imaged when they wore two types of silicone hydrogel lenses ...
Reindel, William T   +2 more
core   +1 more source

Interface‐Directed High Fluorescence Efficiency Two‐Dimensional Molecular Crystals With Surface‐Exposed Active Sites

open access: yesAdvanced Science, EarlyView.
Here, we designed the Me‐FBSe molecule and prepared a two‐dimensional molecular crystal via liquid‐liquid interface assembly. The crystal preserves the high photoluminescence quantum while simultaneously ensuring the high‐density surface exposure of active sites.
Shuya Liu   +6 more
wiley   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

Nematic Liquid Crystal Locking Menisci [PDF]

open access: yes, 2013
We study meniscus driven locking of point defects of nematic liquid crystals confined within a cylindrical tube with free ends. Curvilinear coordinate system is introduced in order to focus on the phenomena of both (convex and concave) types of menisci ...
Slavinec, Mitja   +3 more
core   +1 more source

Hamaker Constants of van der Waals Materials under Clean‐Interface Conditions

open access: yesAdvanced Science, EarlyView.
Clean‐interface adhesion in representative van der Waals materials is quantified by Ultra High Vacuum (UHV) Atomic Force Microscopy (AFM) with in situ cleaning and calibrated probes. Benchmark Hamaker constants for graphene, MoS2, and SiO2 are established, while humidity is shown to reversibly amplify adhesion, explaining much of the scatter in ...
Daniel Gallego‐Fuente   +3 more
wiley   +1 more source

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