Results 41 to 50 of about 526 (163)

Oxoisoaporphine as Potent Telomerase Inhibitor

Molecules, 2016
Two compounds previously isolated from traditional Chinese medicine, Menispermum dauricum (DC), 6-hydroxyl-oxoisoaporphine (H-La), and 4,6-di(2-pyridinyl)benzo[h]isoindolo[4,5,6-de]quinolin-8(5H)-one (H-Lb), were known to have in vitro antitumor activity
Zu-Zhuang Wei, Qi-Pin Qin, Jia-Nian Chen, Zhen-Feng Chen   +3 more
doaj   +1 more source

N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization

Frontiers in Pharmacology, 2017
Resistance of cancer cells to chemotherapy remains a significant problem in oncology. Mechanisms regulating programmed cell death, including apoptosis, autophagy or necrosis, in the treatment of cancers have been extensively investigated over the last ...
Betty Y. K. Law, Simon W. F. Mok, Juan Chen, Francesco Michelangeli, Zhi-Hong Jiang, Yu Han, Yuan Q. Qu, Alena C. L. Qiu, Su-Wei Xu, Wei-Wei Xue, Xiao-Jun Yao, Xiao-Jun Yao, Jia Y. Gao, Masood-ul-Hassan Javed, Paolo Coghi, Liang Liu, Vincent K. W. Wong   +16 more
doaj   +1 more source

Oxoisoaporphines and aporphines: Versatile molecules with anticancer effects [PDF]

, 2019
Indexación: Scopus.Cancer is a disease that involves impaired genome stability with a high mortality index globally. Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity.
Arias-Calderón, M., Cancino, P., Rodríguez-Arce, E., Saldías, M., Silva-Matus, P.   +4 more
core   +1 more source

Identification of Tinomiscium petiolare from Vietnam using the DNA barcode [PDF]

, 2021
Background. Tinomiscium petiolare Hook.f. & Thomson is a medicinal species of the family Menispermaceae. This species is currently being intensively exploited for therapeutic purposes. Precise and rapid identification of T.
B. B. Thinh, H. V. Chinh, L. D. Chac, N. T. Lien, Q. V. Hoi, R. V. Doudkin   +5 more
core   +2 more sources

Dauricine combined with clindamycin inhibits severe pneumonia co-infected by influenza virus H5N1 and Streptococcus pneumoniae in vitro and in vivo through NF-κB signaling pathway

Journal of Pharmacological Sciences, 2018
Dauricine, isolated from Menispermum dauricum, has been widely used for treatment of various diseases, including cardiac ischemia and inflammation-related diseases.
Hui Li, Xin Chen, Shu-Jun Zhou
doaj   +1 more source

Natural plant products in treatment of pulmonary arterial hypertension

Pulmonary Circulation, Volume 8, Issue 3, Page 1-20, July-September 2018., 2018
Pulmonary arterial hypertension (PAH) is a severe disease characterized by progressive remodeling of distal pulmonary arteries and persistent elevation of pulmonary vascular resistance (PVR), which leads to right ventricular dysfunction, heart failure, and eventually death.
Lili Xiang, Ying Li, Xu Deng, Djuro Kosanovic, Ralph Theo Schermuly, Xiaohui Li   +5 more
wiley   +1 more source

Plant Species Disjunctions [PDF]

, 1992
The use of molecular data in the study of plant species disjunctions is reviewed and evaluated. The major reason for employing molecular information is to estimate genetic divergence between morphologically similar disjunct species.
Crawford, Daniel J., Lee, Nam Sook, Stuessy, Tod F.   +2 more
core   +2 more sources

The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer‐Like Pathological Changes In Vitro

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Alzheimer’s disease (AD), the most common neurodegenerative disease, has no effective treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of Menispermum dauricum DC, reportedly has neuroprotective effects in cerebral ischemia.
Pan Liu, Xiao Chen, Haizhe Zhou, Liqun Wang, Zaijun Zhang, Xiaohu Ren, Feiqi Zhu, Yi Guo, Xinfeng Huang, Jianjun Liu, Peter S. Spencer, Xifei Yang, Lisbell Estrada   +12 more
wiley   +1 more source

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

New Journal of Science, Volume 2016, Issue 1, 2016., 2016
Herbal medicines are the oldest and most widely used form of treatment for welfare of mankind. Herbal medicines possess strong reputation as complementary treatment across the globe due to their easy accessibility and safety. Particularly traditional Chinese medicines (TCM) are very popular due to their desirable therapeutic effects.
Piyush Mehta, Vividha Dhapte, Jing-Hsien Chen   +2 more
wiley   +1 more source

СПЕЦИФИКА АДВЕНТИВНОГО КОМПОНЕНТА ФЛОР ФИЗИКО-ГЕОГРАФИЧЕСКИХ ПРОВИНЦИЙ В ПРЕДЕЛАХ ТВЕРСКОЙ ОБЛАСТИ [PDF]

, 2006
Выявлен видовой состав адвентивной флоры фрагментов Верхневолжской, Валдайской, Смоленско-Московской провинций, расположенных в пределах Тверской области.
Колосова, Л.В., Нотов, А.А.   +1 more
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