Results 141 to 150 of about 256,466 (249)

Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats

Aging Cell, Volume 25, Issue 9, September 2026.
Using genetically heterogeneous rats carrying divergent mitochondrial haplotypes on a randomized nuclear background, we show that mtDNA variation modifies the rate of ovarian aging. OKC‐HETW ovaries showed bioenergetic deficits, reduced mtDNA copy number, and impaired TFAM–mtDNA binding by 4 months of age, with early fibrosis and immune infiltration ...
Subhasri Biswas, Hoang V. M. Nguyen, Aubrey Converse, Satoshi Matsuzaki, Michael T. Kinter, Kenneth M. Humphries, Willard M. Freeman, Sarah R. Ocañas, Arlan Richardson, Francesca E. Duncan, Tommy L. Lewis Jr, Michael B. Stout   +11 more
wiley   +1 more source

Time‐Varying Impact of Steatosis and Alcohol on Mortality: A Marginal Structural Model of the Canadian Longitudinal Study on Aging

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims Subclassifications of steatotic liver disease (SLD) are intended to provide a clinically meaningful framework for management. However, steatosis, cardiometabolic comorbidities and alcohol consumption are known to change over time.
Carmela Rapino, Giada Sebastiani, Jessica Burnside, Cindy Wen, Alnoor Ramji, Mark Swain, Keyur Patel, Sahar Saeed   +7 more
wiley   +1 more source

Menopause status and its role in incident Alzheimer's disease and related dementias, rheumatoid arthritis (RA) disease severity, and overall mortality in women with RA. [PDF]

Semin Arthritis Rheum
Salama RS, Hulshizer CA, Crowson CS, Lennon RJ, Rocca WA, George RJ, Frechette N, Allen M, Myasoedova E.   +8 more
europepmc   +1 more source

Premature Menopause [PDF]

, 2020
openaire   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, Volume 111, Issue 9, Page 4015-4040, 1 September 2026.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, Volume 604, Issue 17, Page 7059-7075, 1 September 2026.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Black flesh disorder in mango: a chilling injury symptom increased by early harvest and low storage temperature and reduced by 1‐methylcyclopropene

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6508-6522, 30 August 2026.
Abstract BACKGROUND Black flesh (BF) is an internal disorder in mango, characterized by the development of dark brown to black pigmentation in the inner mesocarp tissue during storage or transport. This study investigated the effects of harvest maturity, low storage or low transport temperatures, and 1‐methylcyclopropene (1‐MCP) on mango fruit ...
Bruna Parente de Carvalho Pires, João Claudio Vilvert, Nilo Ricardo Corrêa de Mello Júnior, Sandy Raiele Sena Monteiro, Mikaele de Souza Santos, Ester Silva Regis, Jackson Teixeira Lobo, Jeffrey K. Brecht, Sergio Tonetto de Freitas   +8 more
wiley   +1 more source

Inflammation-oriented dietary pattern and menopause timing in postmenopausal women: evidence from the Health and Retirement Study. [PDF]

Front Nutr
Liang Y, Huang Z, Li Z, Li H, Lu J, Zhong K, Shi W, Ou Y.   +7 more
europepmc   +1 more source

Hubungan Menopause Dengan Timbulnya Gangguan Depresi Dan Kecemasan Di Pimpinan Daerah Aisyiyah Kota Medan

, 2018
Pendahuluan: Menopause didefenisikan sebagai berhentinya menstruasi secara permanen akibat hilangnya aktifitas folikuler ovarium akibat penuaan yang dimanifestasikan menjadi aminorea 12 bulan secara berturut turut.
Ayu, Azri
core  

Insights into the relationship between menopausal timing and risk of cardiovascular disease: a systematic review and meta-analysis of Mendelian randomization analyses. [PDF]

Syst Rev
Wang Y, Miao X, Withers M, Wong MCS, Viwattanakulvanid P.   +4 more
europepmc   +1 more source