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Primary ovarian insufficiency: update on clinical and genetic findings [PDF]

open access: yesFrontiers in Endocrinology
Primary ovarian insufficiency (POI) is a disorder of insufficient ovarian follicle function before the age of 40 years with an estimated prevalence of 3.7% worldwide.
Silvia Federici   +8 more
doaj   +2 more sources

Endocrinology of Primary Ovarian Insufficiency: Diagnostic and Therapeutic Clues

open access: yesEndocrines
Background: This paper briefly reviews the most important endocrine features of primary ovarian insufficiency (POI) and shows their relevance for the diagnosis and treatment of this condition.
Jan Tesarik
doaj   +1 more source

Roles of Meiotic Defects in Pathogenesis of Primary Ovarian Insufficiency

open access: yesReproductive and Developmental Medicine, 2017
A matured oocyte has experienced three critical division stages: (1) proliferation in early fetal stage, (2) meiotic arrest at diplotene of prophase I, and (3) meiotic resumption and extrusion of the first polar body.
Ling Zhang   +3 more
doaj   +1 more source

Cardiovascular Disease and Primary Ovarian Insufficiency [PDF]

open access: yesSeminars in Reproductive Medicine, 2011
Cardiovascular disease (CVD) is the number-one killer of women. Women with primary ovarian insufficiency (POI) may be more burdened by cardiovascular disease, such as myocardial infarction and stroke, as compared with women with normal menopause.
openaire   +2 more sources

Defying Expectations: A Rare Case of Hypergonadotropic Hypogonadic Pregnancy

open access: yesJournal of Clinical and Diagnostic Research
Amenorrhoea, hypoestrogenism, and hypergonadotropinism are the hallmarks of premature ovarian failure, affecting primary fertility in young females. Hypergonadotropic hypogonadism is a gonadal disorder that delays the onset of puberty in both males and ...
Sridivya Cherukuri   +3 more
doaj   +1 more source

The Role of Platelet-Rich Plasma (PRP) in Enhancing IVF Success in Women With Ovarian Insufficiency: A Cohort Study

open access: yesActa Medica Iranica
Ovarian insufficiency is a significant cause of infertility in women, with limited effective treatment options. Platelet-Rich Plasma (PRP), rich in concentrated growth factors, has shown regenerative potential in various medical fields.
Zahra Mohammad Alipour   +6 more
doaj   +1 more source

FMRP Associates with Cytoplasmic Granules at the Onset of Meiosis in the Human Oocyte.

open access: yesPLoS ONE, 2016
Germ cell development and primordial follicle formation during fetal life is critical in establishing the pool of oocytes that subsequently determines the reproductive lifespan of women.
Roseanne Rosario   +6 more
doaj   +1 more source

Loss of Calponin 2 causes premature ovarian insufficiency in mice

open access: yesJournal of Ovarian Research
Background Premature ovarian insufficiency (POI) is a condition defined as women developing menopause before 40 years old. These patients display low ovarian reserve at young age and difficulties to conceive even with assisted reproductive technology ...
Tzu-Bou Hsieh, Jian-Ping Jin
doaj   +1 more source

Primary ovarian insufficiency and myasthenia gravis.

open access: yesPakistan journal of medical sciences, 2020
Myasthenia gravis (MG) is an autoimmune disease. In some patients, Primary Ovarian Insufficiency (POI) is considered to be an autoimmune condition. Their coexistence is rare and suggests autoimmune perturbation. We describe a patient who was determined to have POI at 17 years of age and who developed MG 20 years later.
openaire   +2 more sources

The effects of acupuncture on patients with premature ovarian insufficiency and polycystic ovary syndrome: an umbrella review of systematic reviews and meta-analyses

open access: yesFrontiers in Medicine
BackgroundPrevious studies have suggested that acupuncture could improve the clinical outcomes of women with premature ovarian insufficiency (POI) and polycystic ovary syndrome (PCOS).
Tianyu Bai   +5 more
doaj   +1 more source

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