Results 1 to 10 of about 4,808,641 (272)

BRCA1, BRCA2 and primary ovarian insufficiency [PDF]

E3S Web of Conferences, 2020
BRCA1 and BRCA2 genes belong to the family of ataxia-telangiectasia-mutated (ATM)-mediated DNA DSB repair genes that play a critical role in the DNA double-strand break (DSB) repair.
Zhang Yinuo
doaj   +2 more sources

Menstrual cycle patterns in primary care: a structured approach using primary ovarian insufficiency as a sentinel condition [PDF]

Frontiers in Medicine
Primary Ovarian Insufficiency, a condition characterized by early loss of ovarian function, illustrates the consequences of failing to act on menstrual cycle changes as early clinical signals.
Lawrence Merle Nelson
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Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis

Analytical Cellular Pathology, 2022
Background. To investigate the relationship between primary ovarian insufficiency and autophagy, we detected and got the expression profile of human granulosa cell line SVOG, which was with or without LPS induced. The expression profile was analyzed with
Siji Lv, Jiani Sun, Jing Sun
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Primary ovarian insufficiency: update on clinical and genetic findings [PDF]

Frontiers in Endocrinology
Primary ovarian insufficiency (POI) is a disorder of insufficient ovarian follicle function before the age of 40 years with an estimated prevalence of 3.7% worldwide.
Silvia Federici, Raffaella Rossetti, Silvia Moleri, Elisabetta V. Munari, Maria Frixou, Marco Bonomi, Marco Bonomi, Luca Persani, Luca Persani   +8 more
doaj   +2 more sources

Stem cell-derived extracellular vesicles: A novel and potential remedy for primary ovarian insufficiency

Frontiers in Cell and Developmental Biology, 2023
Primary ovarian insufficiency (POI) is an essential cause of young female fertility loss. At present, there are many treatments for primary ovarian insufficiency, but due to the complexity of the pathogenesis of primary ovarian insufficiency, the ...
Zixiang Geng, Zixiang Geng, Hailing Guo, Hailing Guo, Yifei Li, Ying Liu, Yongfang Zhao, Yongfang Zhao   +7 more
doaj   +1 more source

Analysis of late-onset ovarian insufficiency after ovarian surgery: retrospective study with 75 patients of post-surgical ovarian insufficiency. [PDF]

PLoS ONE, 2014
The primary objectives of the present study are to determine the period of onset of ovarian insufficiency after surgery and to confirm potential risk factors for ovarian insufficiency after surgery for the removal of benign ovarian cysts.
Seido Takae, Kazuhiro Kawamura, Yorino Sato, Chie Nishijima, Nobuhito Yoshioka, Yodo Sugishita, Yuki Horage, Mamoru Tanaka, Bunpei Ishizuka, Nao Suzuki   +9 more
doaj   +1 more source

Early postnatal alterations in follicular stress response and survival in a mouse model of Classic Galactosemia

Journal of Ovarian Research, 2022
Primary ovarian insufficiency is characterized by accelerated loss of primordial follicles, which results in ovarian failure and concomitant menopause before age 40. About 1–3% of females in the general population are diagnosed with POI; however, greater
Synneva Hagen-Lillevik, Joshua Johnson, Kent Lai   +2 more
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Primary ovarian insufficiency quality of life scale (POIQOLS): development and psychometric properties

BMC Women's Health, 2022
Background Primary ovarian insufficiency is menopause before the age of 40. It can affect the quality of life of afflicted women. Because there is no instrument available for measuring the quality of life of these women, the present study was carried out
Samira Golezar, Zohreh Keshavarz, Fahimeh Ramezani Tehrani, Abbas Ebadi, Farid Zayeri, Mohammad Hossein Golezar   +5 more
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Case Report: Is It Premature Ovarian Insufficiency or Swyer Syndrome After Bone Marrow Transplantation?

Frontiers in Pediatrics, 2022
Introduction: Iatrogenic factor is one of the recognized causes for premature ovarian insufficiency. The aim of this case report was to present a rare case with premature ovarian insufficiency and 46, XY karyotype after bone marrow transplant (BMT) for ...
Hui Li, Jin Li, Xiaohong Li, Hong Yi, Qixiu Ren, Xiaoyan Chen, Xiaoyan Chen   +6 more
doaj   +1 more source

BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency

Nature Communications, 2022
Primary ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction that results in infertility. Here they show that BCN1 mutation results in premature ovarian follicle activation and atresia through dysregulation of ferroptosis.
Feixia Wang, Yifeng Liu, Feida Ni, Jiani Jin, Yiqing Wu, Yun Huang, Xiaohang Ye, Xilin Shen, Yue Ying, Jianhua Chen, Ruixue Chen, Yanye Zhang, Xiao Sun, Siwen Wang, Xiao Xu, Chuan Chen, Jiansheng Guo, Dan Zhang   +17 more
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