Results 11 to 20 of about 4,572,451 (270)

Genetics of primary ovarian insufficiency [PDF]

Clinical Genetics, 2016
Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the age of 40 and account for one major cause of female infertility. POI relevance is continuously growing because of the increasing number of women desiring conception beyond 30 years of age, when POI prevalence is >1%.
ROSSETTI, RAFFAELLA, FERRARI, ILARIA, M. Bonomi, L. Persani   +3 more
openaire   +3 more sources

Primary Ovarian Insufficiency in RMND1 Mitochondrial Disease

Endocrine Abstracts, 2022
RMND1 (Required for Meiotic Nuclear Division 1 homolog) is a nuclear encoded mitochondrial protein. Biallelic variants inRMND1are described in patients with white matter encephalopathy, hearing loss and renal dysfunction. In addition to this phenotype, two independent families (3 patients) have been reported with ovarian failure. We report on a 17-year-
E. Boros, F. Elilié Mawa Ongoth, C. Heinrichs, A.L. Mansbach, S. Seneca, A. Aeby, K. Ismaïli, C. Brachet   +7 more
openaire   +4 more sources

A design thinking approach to primary ovarian insufficiency.

, 2017
Most clinicians are not prepared to provide integrated personal care to address all the clinical needs of women with primary ovarian insufficiency. Design thinking is an engineering methodology used to develop and evaluate novel concepts for systems ...
Jiang, Xuezhi, Porter, Alison G, Hall, Janet E, Rajkovic, Aleksandar, Fair, Ryan, Schnatz, Peter F, Kleinstreuer, Nicole, Pelligrini, Vincent A, Verbiest, Sarah, Olmstead, Jill, Rachel\u27s Well Primary Ovarian Insufficiency Community of Practice Group, Nelson, Lawrence M, Persani, Luca, Falorni, Alberto, Mehta, Khanjan, Martin, Lisa A   +15 more
core   +4 more sources

Primary ovarian insufficiency quality of life scale (POIQOLS): development and psychometric properties

BMC Women's Health, 2022
Background Primary ovarian insufficiency is menopause before the age of 40. It can affect the quality of life of afflicted women. Because there is no instrument available for measuring the quality of life of these women, the present study was carried out
Samira Golezar, Zohreh Keshavarz, Fahimeh Ramezani Tehrani, Abbas Ebadi, Farid Zayeri, Mohammad Hossein Golezar   +5 more
doaj   +1 more source

Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis

Analytical Cellular Pathology, 2022
Background. To investigate the relationship between primary ovarian insufficiency and autophagy, we detected and got the expression profile of human granulosa cell line SVOG, which was with or without LPS induced. The expression profile was analyzed with
Siji Lv, Jiani Sun, Jing Sun
doaj   +1 more source

Case Report: Is It Premature Ovarian Insufficiency or Swyer Syndrome After Bone Marrow Transplantation?

Frontiers in Pediatrics, 2022
Introduction: Iatrogenic factor is one of the recognized causes for premature ovarian insufficiency. The aim of this case report was to present a rare case with premature ovarian insufficiency and 46, XY karyotype after bone marrow transplant (BMT) for ...
Hui Li, Jin Li, Xiaohong Li, Hong Yi, Qixiu Ren, Xiaoyan Chen, Xiaoyan Chen   +6 more
doaj   +1 more source

Update on primary ovarian insufficiency [PDF]

Current Opinion in Endocrinology, Diabetes & Obesity, 2015
Despite an incidence of 1% among women under the age of 40, primary ovarian insufficiency (POI) is still poorly understood. As the variable cause and presentation of POI complicate its management, a standard regimen for treatment remains to be established.
Meghan, Hewlett, Shruthi, Mahalingaiah
openaire   +2 more sources

BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency

Nature Communications, 2022
Primary ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction that results in infertility. Here they show that BCN1 mutation results in premature ovarian follicle activation and atresia through dysregulation of ferroptosis.
Feixia Wang, Yifeng Liu, Feida Ni, Jiani Jin, Yiqing Wu, Yun Huang, Xiaohang Ye, Xilin Shen, Yue Ying, Jianhua Chen, Ruixue Chen, Yanye Zhang, Xiao Sun, Siwen Wang, Xiao Xu, Chuan Chen, Jiansheng Guo, Dan Zhang   +17 more
doaj   +1 more source

Gonadotropin-Resistant Ovary Syndrome Presented with Secondary Amenorrhea and Infertility: A Case Report [PDF]

Iranian Journal of Medical Sciences, 2020
Resistant ovary syndrome (ROS) is a presentation of hypergonadotrophic hypogonadism condition with very low incidence. Infertility is one of the most common complaints of women with this syndrome.
Alamtaj Samsami, Sara Davoodi, Leila Ghasmpour, Shaghayegh Moradi Alamdarloo, Jamshid Rahmati, Ali Karimian   +5 more
doaj   +1 more source

Menarche in primary ovarian insufficiency after a month of hormone replacement therapy: a case report

Journal of Medical Case Reports, 2021
Background Gynecologic anomalies, including uterine agenesis and ovarian dysgenesis, are some of the several differential diagnoses in adolescent females with primary amenorrhea and delayed puberty.
Biwen Cheng
doaj   +1 more source