Earlier Age at Menopause, Plasma Metabolome, and Risk of Premature Mortality
Background/Objectives: Menopause and related metabolites are associated with mortality. However, the relationship between earlier menopause, premature mortality, and the role of metabolomic signatures remains underexplored.
Zeping Yang +10 more
doaj +1 more source
Premature and normal menopause: an evaluation in terms of stress, marital adjustment and sex roles [PDF]
Objective: Middle age period brings about particular difficulties for some women, because of the physiological and psychological changes. The physiological changes occuring in this period is called andropause for males and menopause for females. While it
meral onder, aysegul durak batigun
doaj
BackgroundTransition into menopause is associated with an increased risk of cardiovascular disease (CVD). However, it is unclear whether the association exists between premature menopause (defined as age at menopause 40 years) or early menopause (defined
Jiajun Liu +6 more
doaj +1 more source
Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper. [PDF]
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Benedetto C +8 more
europepmc +2 more sources
Possible association between subclinical hypothyroidism and age at menopause in Colombian women
Objective To evaluate the association between subclinical hypothyroidism with early menopause, premature menopause, and last menstrual bleeding before the natural age of menopause.Methods This was a cross-sectional study conducted in 643 postmenopausal ...
Álvaro Monterrosa-Castro +2 more
doaj +1 more source
Background: Premature menopause, defined as natural menopause before age 40, is associated with diminished ovarian reserve. Despite growing concerns regarding environmental pollutants, no large-scale population-based studies have systematically examined ...
Qian Yang +5 more
doaj +1 more source
Background Chemotherapy can cause premature menopause which may result in adverse effects such as fertility loss, osteoporosis, cardiovascular disease and menopausal symptoms.
Hilary Laura Martin +10 more
doaj +1 more source
Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort. [PDF]
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Wang M +6 more
europepmc +2 more sources
Building families—Implementing balanced sexual and reproductive health
Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu +9 more
wiley +2 more sources
Early Menopause in Type 2 Diabetes – A Study from a South Indian Tertiary Care Centre [PDF]
Introduction: Menopause marks the end of ovarian function and it is called ‘early’ or ‘premature’ if it occurs before 45 years. Very little is known about the menopause transition in Diabetic women.
T.V.D. Sasi Sekhar +3 more
doaj +1 more source

