Results 61 to 70 of about 412,507 (379)

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study [PDF]

, 2007
BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS:We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) for longevity-related traits in a ...
Benjamin, Emelia J, D'Agostino, Ralph B, Govindaraju, Raju, Guo, Chao-Yu, Karasik, David, Kelly-Hayes, Margaret, Kiel, Douglas P, Lunetta, Kathryn L, Massaro, Joseph M, Murabito, Joanne M, Pencina, Michael J, Seshadri, Sudha   +11 more
core   +6 more sources

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

The role of Phytoestrogens in the management of menopausal symptoms [PDF]

, 2012
Menopause reflects a change in the woman’s physiological hormonal status and is regarded as a pivotal point in a woman’s life. The commonest symptoms experienced by women during the menopause are hot flushes and night sweats.
Avendonk, Tania van
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Current insights into gonadotropic pituitary function in the polycystic ovary syndrome

Asian Pacific Journal of Reproduction, 2014
Objective: To assess the gonadotrope cell function in patients with polycystic ovary syndrome (PCOS). Methods: This study included 42 patients with polycystic ovary syndrome, aged 26.6 ± 5.9 years, and 13 eumenorrheic controls, aged 30.1 ± 4.6 years ...
Cristianne Serafim da Silva Feuser, Jacklyne Silva Barbosa, Evelyn Barzotto da Silva, Sebastião Freitas de Medeiros   +3 more
doaj   +1 more source

Factors of induced and noninduced menopause in India

BLDE University Journal of Health Sciences, 2021
BACKGROUND: In recent years, hysterectomy has received increased attention in health policy debates in India. The objective of the study was to examine induced and noninduced menopause and its associated factors among menopause women in India.
Rajeshwari Annappa Biradar, Jang Bahadur Prasad, Renuka E Asagi   +2 more
doaj   +1 more source

Changes in body composition and weight during the menopause transition.

JCI Insight, 2019
BACKGROUND The relation between the menopause transition (MT) and changes in body composition or weight remains uncertain. We hypothesized that, independent of chronological aging, the MT would have a detrimental influence on body composition.
G. Greendale, B. Sternfeld, Mei-hua Huang, Weijuan Han, C. Karvonen-Gutierrez, K. Ruppert, J. Cauley, J. Finkelstein, Sheng-fang Jiang, A. Karlamangla   +9 more
semanticscholar   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Severe mental illness and the perimenopause

BJPsych Bulletin
Hormonal fluctuations in the perimenopause are associated with an array of physical and psychological symptoms. Those with pre-existing mental disorders may experience changes to their symptoms and response to treatment during the perimenopausal and ...
Sophie Behrman, Clair Crockett
doaj   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source