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Dysregulation of myddosome complex genes its related to alendronate treatment failure in osteoporosis postmenopausal patients. [PDF]

open access: yesGenet Mol Biol
Some patients with osteoporosis (OP) do not respond to treatment with bisphosphonates; pathways that stimulate osteoclatogenesis may be involved in this failure, such as the myddosome pathway.
Oliveira BMR   +5 more
europepmc   +2 more sources

Three Classes of Antioxidant Defense Systems and the Development of Postmenopausal Osteoporosis

open access: yesFrontiers in Physiology, 2022
Osteoporosis is a common bone imbalance disease that threatens the health of postmenopausal women. Estrogen deficiency accelerates the aging of women. Oxidative stress damage is regarded as the main pathogenesis of postmenopausal osteoporosis.
Keda Yang   +4 more
doaj   +2 more sources

The prevalence and treatment rate trends of osteoporosis in postmenopausal women.

open access: yesPLoS ONE, 2023
BackgroundTo evaluate the prevalence and treatment of postmenopausal women with osteoporosis in recent years, analyze differences between the prevalence diagnosed by physicians and the prevalence detected by bone mineral density (BMD), and observe the ...
Xiaojuan Zhang   +6 more
doaj   +2 more sources

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

open access: yesFrontiers in Pharmacology, 2023
Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women. The association between these two diseases are evident through systemic bone loss and alveolar bone loss.
Putri Ayu Jayusman   +5 more
doaj   +2 more sources

Prevalence and diagnosis experience of osteoporosis in postmenopausal women over 50: Focusing on socioeconomic factors.

open access: yesPLoS ONE, 2021
Osteoporosis is the most common disease of the musculoskeletal system in old age. Therefore, research on osteoporosis risk factors is actively being conducted.
Min Hyeok Choi   +4 more
doaj   +2 more sources

The relationship between the monocyte-to-lymphocyte ratio and osteoporosis in postmenopausal females with T2DM: A retrospective study in Chinese population

open access: yesFrontiers in Endocrinology, 2023
IntroductionThe risk of fragility fractures is increased in patients with type 2 diabetes mellitus (T2DM). Many reports indicate that inflammatory and immune responses are associated with osteoporosis and osteopenia. The monocyte-to-lymphocyte ratio (MLR)
Hailin Li   +6 more
doaj   +1 more source

Metabolomics-based analysis of plasma in postmenopausal women with normal bone mineral density, postmenopausal osteoporosis, and rheumatoid arthritis osteoporosis

open access: yesAll Life, 2023
This study aimed to examine metabolites in the plasma derived from postmenopausal women by untargeted metabolomics along with possible diagnostic markers for osteoporosis.
Kun Zhu   +5 more
doaj   +1 more source

Asia–pacific consensus on osteoporotic fracture prevention in postmenopausal women with low bone mass or osteoporosis but no fragility fractures

open access: yesJournal of the Formosan Medical Association, 2023
Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, with 25% developing a spine deformity and 15% developing
Chun-Feng Huang   +25 more
doaj   +1 more source

Postmenopausal osteoporosis coexisting with sarcopenia: the role and mechanisms of estrogen.

open access: yesJournal of Endocrinology, 2023
Estrogens (estradiol, estriol, and estrone) are important hormones that directly and indirectly regulate the metabolism and function of bone and skeletal muscle via estrogen receptors.
Lingyun Lu, L. Tian
semanticscholar   +1 more source

Identification of miR-194-5p as a potential biomarker for postmenopausal osteoporosis [PDF]

open access: yesPeerJ, 2015
The incidence of osteoporosis is high in postmenopausal women due to altered estrogen levels and continuous calcium loss that occurs with aging. Recent studies have shown that microRNAs (miRNAs) are involved in the development of osteoporosis.
Jia Meng   +8 more
doaj   +2 more sources

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