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Long-Term Treatment of Postmenopausal Osteoporosis
Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate ...
Jacques P. Brown
semanticscholar +1 more source
T-Cell Mediated Inflammation in Postmenopausal Osteoporosis
Osteoporosis is the most prevalent metabolic bone disease that affects half the women in the sixth and seventh decade of life. Osteoporosis is characterized by uncoupled bone resorption that leads to low bone mass, compromised microarchitecture and ...
Di Wu +5 more
semanticscholar +1 more source
Objectives We investigated the role of long non-coding (lnc) RNA-NEF (neighboring enhancer of FoxA2), a characterized oncogene in cancer biology, in postmenopausal osteoporosis and its diagnostic and prognostic value in this disease.
Xiaoyong Ma +9 more
doaj +1 more source
Introduction Osteoporosis is a significant clinical and public health concern worldwide. Despite the impact of this condition on women's lives, most studies have focused on its clinical manifestations, drug efficacy, and medical treatment.
Faiza Al Zadjali +3 more
doaj +1 more source
Importance The clinical decision to initiate bisphosphonate therapy for the treatment of osteoporosis requires balancing shorter-term harms and burdens (eg, gastroesophageal irritation or severe musculoskeletal pain) with longer-term benefits in reducing
W. Deardorff +3 more
semanticscholar +1 more source
Objective. To demonstrate the role of Wnt/β-catenin canonical pathway in postmenopausal osteoporosis by evaluating serum β-catenin levels in patients with postmenopausal osteoporosis and analyzing their possible relationship with serum OPG, RANKL, the ...
Xiao-Juan Xu +6 more
doaj +1 more source
Background Osteoporosis affects mostly postmenopausal women, leading to deterioration of the microarchitectural bone structure and low bone mass, with an increased fracture risk with associated disability, morbidity and mortality.
Filippo Migliorini +5 more
semanticscholar +1 more source
Biomarkers as therapy monitoring for postmenopausal osteoporosis: a systematic review
Biochemical markers of bone turnover (BTMs), such as bone alkaline phosphatase (bALP), procollagen type I N propeptide (PINP), serum cross-linked C-telopeptides of type I collagen (bCTx), and urinary cross-linked N-telopeptides of type I collagen (NTx ...
Filippo Migliorini +5 more
semanticscholar +1 more source
Objective: The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the
Pauline M. Camacho +13 more
semanticscholar +1 more source
Background: Osteoporosis is an illness that may be categorized as a "silent pandemic" because of its worldwide incidence. The essential characteristics of osteoporosis are bone mass reduction and degeneration in bone tissue's micro-architecture ...
Raed Farooq Khaleel , +2 more
doaj +1 more source

