Results 81 to 90 of about 290,506 (328)

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

Advanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li, Bingqing Gong, Zichen Song, Nuo Yang, Yuming Liu, Jinqin Zhang, Dujuan Li, Yongyan Yang, Yonghao Yu   +8 more
wiley   +1 more source

Factors Influencing Uptake of Risk-Reducing Salpingo-Oophorectomy by BRCA1 and BRCA2 Mutation Carriers [PDF]

, 2016
Germline mutations in the BRCA1 and BRCA2 genes are associated with significantly increased risks for ovarian cancer. The National Comprehensive Cancer Network (NCCN) currently recommends that female BRCA mutation carriers undergo risk-reducing salpingo ...
Breen, Victoria E
core   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source

Evidence for Action on HIV Treatment and Care Systems in low and middle-income countries: background and introduction.

, 2012
Despite the unprecedented scale-up of treatment for HIV in low and middle-income countries over the past decade, 49% of adults and 77% of children in need of HIV treatment still do not have access to it.
Hakim, James, Ross, David A, South, Annabelle, Weller, Ian   +3 more
core   +1 more source

Active Whisker‐Inspired Food Material Surface Property Measurement Using Deep‐Learned Mechanosensor

Advanced Intelligent Systems, EarlyView.
Herein, a new application is proposed for an active whisker sensor that mimics the movement of rat whiskers. The whiskers, which are deformed by contact with an object, provide information about surface properties. It is shown that active whisker sensors can be useful in the food industry, and data identification is performed using deep learning ...
Jieun Park, Minho Kim, Jinhyung Park, Myungrae Hong, Sunghoon Im, Damin Choi, Eunyoung Kim, Dohyeon Gong, Seokhaeng Huh, Seung‐Un Jo, ChangHwan Kim, Je‐Sung Koh, Seungyong Han, Daeshik Kang   +13 more
wiley   +1 more source

Possible association between subclinical hypothyroidism and age at menopause in Colombian women

Gynecological Endocrinology
Objective To evaluate the association between subclinical hypothyroidism with early menopause, premature menopause, and last menstrual bleeding before the natural age of menopause.Methods This was a cross-sectional study conducted in 643 postmenopausal ...
Álvaro Monterrosa-Castro, Angelica Monterrosa-Blanco, Sandra Sánchez-Zarza   +2 more
doaj   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

Peran Religiusitas Mengatasi Kecemasan Masa Menopause [PDF]

, 2012
Masa menopause adalah hal yang alamiah dan tidak terelakkan pada setiap perempuan yang memasuki usia 50. Di saat memasuki masa menopause, perempuan mengalami Perubahan penting dalam kehidupannya.
Firmiana, M. E. (Masni), Imawati, R. (Rochimah), Prasetya, M. R. (Meithya)   +2 more
core   +2 more sources

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source

Women's decision making process about hormone replacement therapy in the New Zealand context : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 2003
Some Appendix in MaoriThe transitional time of menopause has differential meanings for mid-aged women around the world. The medicalisation of menopause has resulted in the increasing promotion of hormone replacement therapy (HRT) both to alleviate ...
Radford, Wendy Lena
core