Results 111 to 120 of about 1,050,766 (318)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Altered Structure-Function Coupling Associated with Attention Decline in Shift Work Disorder

open access: yesNature and Science of Sleep
Ziyao Wu,1,2,* Sitong Feng,1,2,* Kuangshi Li,3,* Linrui Dong,4 Liang Zhang,1,2 Yanzhe Ning,1,2 Dongqing Yin1,2 1Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National ...
Wu Z   +6 more
doaj  

Longitudinal trajectories of subjective cognitive complaints in patients with major depressive disorder and similar objective cognitive trajectories

open access: yesBMC Psychiatry
Background We examined the factors influencing various subtypes of subjective cognitive change in patients who shared similar objective cognitive trajectories within 6 months.
Xuequan Zhu   +4 more
doaj   +1 more source

Hypertension and common mental disorders in a nationally-representative sample of South African adults

open access: yes, 2007
Includes bibliographical references (leaves 96-98).This thesis examines the associations between self-reported hypertension diagnosis and Diagnostic and Statistical Manual of Mental Disorders 4th edition (DSM-IV) defined a) anxiety disorders b ...
Grimsrud, Anna
core  

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Altered Cerebro-Cerebellar Functional Connectivity Associated With Working Memory Decline After Sleep Deprivation

open access: yesJournal of Integrative Neuroscience
Background: It has been demonstrated that the cerebellum plays a critical role not only in motor function but also in cognitive function.
Ziyao Wu   +5 more
doaj   +1 more source

Lifestyle choices and mental health : a representative population survey [PDF]

open access: yes, 2014
Background: Identifying healthy lifestyle behaviours that promote psychological wellbeing is crucial to preventing mental disorders. The aim of the current study was to evaluate the individual and combined associations between different aspects of ...
Zhang, Xiao-Chi   +13 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Objective diagnosis and treatment outcome prediction in major depressive disorder based on a machine learning framework with dried-serum NIRS digital biomarkers

open access: yesBMC Psychiatry
Background Major depressive disorder (MDD) involves complex interactions across multiple physiological systems, necessitating a comprehensive and integrative perspective for objective diagnosis and personalized treatment.
Mingxia Liu   +4 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

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