Results 91 to 100 of about 1,050,766 (318)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Contribution of resting-state functional connectivity of the subgenual anterior cingulate to prediction of antidepressant efficacy in patients with major depressive disorder

Translational Psychiatry
This study investigated how resting-state functional connectivity (rsFC) of the subgenual anterior cingulate cortex (sgACC) predicts antidepressant response in patients with major depressive disorder (MDD).
Yun Wang, Changshuo Wang, Jingjing Zhou, Xiongying Chen, Rui Liu, Zhifang Zhang, Yuan Feng, Lei Feng, Jing Liu, Yuan Zhou, Gang Wang   +10 more
doaj   +1 more source

Improving the outcomes of primary care attenders with common mental disorders in developing countries: a cluster randomized controlled trial of a collaborative stepped care intervention in Goa, India [PDF]

, 2008
Background and Objective: Common mental disorders (CMD) are a leading global burden of disease. Up to 30% of primary care attenders suffer from these disorders but most do not receive evidence-based drug or psychological treatments.
Ricardo Araya, Simon, G, Gregory Simon, Chisholm, D, Weiss, H, Sulochana Pednekar, Weiss Helen, Pednekar, S, Chisholm, Daniel, Kirkwood, BR, Daniel Chisholm, Helen Weiss, Patel Vikram H, Simon, Gregory, Weiss, Helen, Araya Ricardo, King, M, Pednekar, Sulochana, Simon Gregory, Chisholm Daniel, Araya, Ricardo, Araya, R, Kirkwood Betty R, Betty R Kirkwood, Kirkwood, Betty R, King, Michael, Patel, VH, King Michael, Michael King, Patel, Vikram H, Vikram H Patel, Pednekar Sulochana   +31 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Investigating seasonal metabolic variations in bipolar disorder: a targeted metabolomics study

BMC Psychiatry
Background Bipolar disorder (BD) is a severe mental illness characterized by seasonal episodes, yet its metabolic basis remains unclear. Methods This study utilized targeted metabolomics to investigate seasonal metabolic changes.
Xue Li, Xinzi Liu, Ziyan Li, Sitong Feng, Sisi Zheng, Hongxiao Jia, Dongqing Yin   +6 more
doaj   +1 more source

Towards a functional model of mental disorders incorporating the laws of thermodynamics [PDF]

, 2013
The current paper presents the hypothesis that the understanding of mental disorders can be advanced by incorporating the laws of thermodynamics, specifically relating to energy conservation and energy transfer.
Karen McKenzie, George C. Murray, McKenzie, Karen, Murray, George   +3 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Sex differences in fecal metabolic profiles of major depressive disorder: unveiling sex-specific metabolomic panel

BMC Psychiatry
Background Major depressive disorder (MDD) disproportionately affects women, who exhibit a higher prevalence and greater symptom severity than men. However, sex-specific pathophysiological mechanisms remain poorly understood. Emerging evidence implicates
Siyu Ren, Peilin Qin, Yaping Wang, Zhiyu Li, Zuoli Sun, Gang Wang, Jian Yang   +6 more
doaj   +1 more source

Study on the application of STEAM education in clinical teaching of psychoneurologic interdisciplinary

Guoji laonian yixue zazhi
With the development of the times, the development of interdisciplinary integration is more and more important, and cultivating high-quality medical talents with interdisciplinary practical ability is an important goal and demand for the development of ...
Li Yan, Wang Xuechu, Li Fengjuan, Zhou Chang, Wang Yue, Dong Kai   +5 more
doaj   +1 more source

Association of socio-economic, gender and health factors with common mental disorders in women: a population-based study of 5703 married rural women in India. [PDF]

, 2010
BACKGROUND: There are few population-based studies from low- and middle-income countries that have described the association of socio-economic, gender and health factors with common mental disorders (CMDs) in rural women.
R. Shidhaye, V. Patel, Patel, Vikram, Shidhaye, Rahul   +3 more
core   +1 more source