Results 71 to 80 of about 914,522 (268)

The Chinese version of the immediate mood scaler (IMS): a study evaluating its validity, reliability, and responsiveness in patients with MDD in China

BMC Psychiatry
Background It is important to timely capture the fluctuation of the symptoms related to major depressive disorder (MDD). However, most conventionally used assessment tools for MDD symptoms are not designed for real-time assessment.
Xiongying Chen, Zizhao Feng, Nanxi Li, Le Xiao, Xu Chen, Xuequan Zhu   +5 more
doaj   +1 more source

Scopolamine augmentation of a newly initiated escitalopram treatment for major depressive disorder: study protocol for a randomized controlled trial

Trials, 2019
Background Major depressive disorder (MDD) is a prevalent and disabling disorder that can lead to heavy individual, familial, and societal burdens. Although pharmaceutical interventions still play an essential role in therapeutic measures, limitations ...
Jingjing Zhou, Weiwei Wang, Jian Yang, Xuequan Zhu, Lei Feng, Le Xiao, Gang Wang   +6 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Longitudinal trajectories of subjective cognitive complaints in patients with major depressive disorder and similar objective cognitive trajectories

BMC Psychiatry
Background We examined the factors influencing various subtypes of subjective cognitive change in patients who shared similar objective cognitive trajectories within 6 months.
Xuequan Zhu, Xiongying Chen, Yuanzhen Wu, Lei Feng, Xu Chen   +4 more
doaj   +1 more source

Suicide and mental disorders [PDF]

Tidsskrift for Den norske legeforening, 2014
Heidi, Hjelmeland, Gudrun, Dieserud, Kari, Dyregrov, Birthe Loa, Knizek, Mette Lyberg, Rasmussen   +4 more
openaire   +2 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Objective diagnosis and treatment outcome prediction in major depressive disorder based on a machine learning framework with dried-serum NIRS digital biomarkers

BMC Psychiatry
Background Major depressive disorder (MDD) involves complex interactions across multiple physiological systems, necessitating a comprehensive and integrative perspective for objective diagnosis and personalized treatment.
Mingxia Liu, Yaping Wang, Yi He, Zuoli Sun, Jian Yang   +4 more
doaj   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

Altered Cerebro-Cerebellar Functional Connectivity Associated With Working Memory Decline After Sleep Deprivation

Journal of Integrative Neuroscience
Background: It has been demonstrated that the cerebellum plays a critical role not only in motor function but also in cognitive function.
Ziyao Wu, Sitong Feng, Sisi Zheng, Linrui Dong, Hongxiao Jia, Yanzhe Ning   +5 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source