Results 61 to 70 of about 1,050,766 (318)

Real-world evidence from a retrospective study on suicide during depression: clinical characteristics, treatment patterns and disease burden

BMC Psychiatry
Background Suicide stands as both a primary symptom and the direst outcome of major depressive disorder (MDD). The scarcity of effective treatment strategies makes managing MDD patients with suicide especially challenging.
Han Wang, Nan Lyu, Juan Huang, Bingbing Fu, Lili Shang, Fan Yang, Qian Zhao, Gang Wang   +7 more
doaj   +1 more source

Risk factors for osteoporosis in chronic schizophrenia on long-term treatment with antipsychotics: a cross-sectional study

BMC Psychiatry, 2023
Background Little is known about the laboratory variable risks with bone mineral density (BMD) in patients with schizophrenia. This study was designed to fully investigate the related risk factors for decreased BMD in schizophrenia, as well as evaluate ...
Furu Liu, Ying Wu, Jindong Chen, Tianxiang Zou, Yue Qin, Ziwei Teng, Yuhan Su, Renrong Wu, Jing Huang   +8 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Temporal integration window of sensory processing as a neuropsychological marker for clinical high risk of psychosis

Schizophrenia
Early identification of individuals with clinical high risk (CHR) for psychosis relies heavily on subjective assessments, necessitating the exploration of objective markers to enhance diagnostic accuracy.
Shuo Lin, Lu Tian, Wei-hao Tan, Li-na Wang, Wei-gang Pan, Li Li, Yi Liu, Chao-meng Liu, Han Wu, Wen Wang, Wen-qing Jin, Yi-lang Tang, Yan-ping Ren, Xin Ma   +13 more
doaj   +1 more source

The effects of childhood trauma on personality in unaffected first-degree relatives of patients with major depressive disorder

BMC Psychiatry, 2022
Abstrac Objectives This study aimed to preliminarily and exploratorily examine the associations between childhood trauma (CT), its subtypes, and personality traits among unaffected first-degree relatives (FDR, children, or siblings) of patients with ...
Yu-jie Wen, Qi-jing Bo, Wen-peng Hou, Zhen Mao, Feng Li, Fan He, Fang Dong, Xin Ma, Yi-lang Tang, Xian-bin Li, Chuan-yue Wang   +10 more
doaj   +1 more source

Comorbidity of infectious diseases and anxiety disorders in adults and its association with quality of life: a community study [PDF]

, 2014
Infectious diseases and anxiety disorders are common and both are associated with substantial burden to individual, families, and society. A better understanding of their association may be helpful in explicating possible etiological mechanisms related ...
Meyer, Andrea Hans, Goodwin, Renee D., Andrew T. Gloster, Lieb, Roselind, Renee D Goodwin, Cornelia Witthauer, Roselind eLieb, Roselind Lieb, Witthauer, Cornelia, Gloster, Andrew T., Renee D. Goodwin, Cornelia eWitthauer, Andrea Hans Meyer   +12 more
core   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Dysfunctional large-scale brain networks in drug-naïve depersonalization-derealization disorder patients

BMC Psychiatry
Background Depersonalization-Derealization Disorder (DPRD) presents challenges in understanding its neurobiological underpinnings. Several neuroimaging studies have revealed altered brain function and structure in DPRD. However, the knowledge about large-
Sisi Zheng, Mingkang Song, Nan Song, Hong Zhu, Xue Li, Dongqing Yin, Shanshan Liu, Yan Zhao, Meng Fang, Yanzhe Ning, Hongxiao Jia   +10 more
doaj   +1 more source

What’s wrong with ‘mental’ disorders? : a commentary on ‘What is a mental/psychiatric disorder? : from DSM-IV to DSM-V’ by Stein et al [PDF]

, 2010
The editorial by Stein et al. (2010) is timely and relevant given the development of DSM-V and the likely impact that such a development will have on mental health services in the USA.
Bortolotti L, Broome, Matthew R., Bortolotti, L.; id_orcid, Bortolotti, L, Bortolotti, Lisa, Broome, Matthew, Bortolotti, L., Broome M, Broome, M.; id_orcid, Broome, M.   +9 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source