Results 131 to 140 of about 4,816,387 (353)

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Physical Therapy of Mental Disorder [PDF]

, 1947
Donald W. Winnicott
openalex   +3 more sources

THE INCIDENCE OF MENTAL DISORDER [PDF]

, 1935
Eliot Slater
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Decreased dynamic variability of the cerebellum in the euthymic patients with bipolar disorder

BMC Psychiatry
Background Bipolar disorder (BD) is a complex mental illness characterized by different mood states, including depression, mania/hypomania, and euthymia.
Zhenzhu Chen, Zhifang Zhang, Feng Li, Lei Zhao, Qijing Bo, Yuan Zhou, Chuanyue Wang   +6 more
doaj   +1 more source

Mental Disorder Associated with Primary Lung Carcinoma [PDF]

, 1956
Fred Charatan, J. B. Brierley
openalex   +1 more source

Dual‐Working‐Pattern Nanosheet‐Based Hydrogel Sensors for Constructing Human‐Machine and Physiological‐Electric Interfaces

Advanced Science, EarlyView.
Hydrogels hold great potential as candidates for next‐generation epidermal electronics; however, an unresolved issue remains: the differentiation and selection of sensing modes in hydrogel sensors. This study integrates series‐parallel conductive nanosheet configurations into an ultra‐soft hydrogel, resulting in enhanced signal intensity and ...
Shitao Shi, Yuanyuan Wang, Zewei Ye, Hongxia Xie, Chencong Liu, Jiaqi Liao, Dawei Zhao, Qingfeng Sun, Julia L. Shamshina, Xiaoping Shen   +9 more
wiley   +1 more source

AN INTRODUCTION TO THE STUDY OF MENTAL DISORDERS.

, 1924
Francis Merriman Barnes
openalex   +3 more sources

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Common Mental Disorders

Kathmandu University Medical Journal, 2012
Common mental disorders are a group of distress states manifesting with anxiety, depressive and unexplained somatic symptoms typically encountered in community and primary care settings. Risk factors for these disorders are mainly lower socio-economic status, psychological illnesses, poor reproductive health, gender disadvantage and physical ill-health.
openaire   +4 more sources