Results 171 to 180 of about 1,762,410 (305)

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

N6-methyladenosine methylation: a novel key to unlocking mental disorders. [PDF]

Int J Neuropsychopharmacol
Wang Y, Li X, Liu M, Xu X, Ma Y, Luo Y, Wang Y.   +6 more
europepmc   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

Advanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S Sutcliffe, Yi Jiang, Ying Ji, Chunyu Liu, Feixiong Cheng, Edwin H Cook, Nancy J Cox, Xue Zhong, Zhexing Wen, Bingshan Li   +15 more
wiley   +1 more source

Determinants of sibling relationships in the context of mental disorders. [PDF]

PLoS One
Lecciso F, Martis C, Del Prete CM, Martino P, Primiceri P, Levante A.   +5 more
europepmc   +1 more source

An Automated Micro‐Immunobeads‐Based Electromagnetic Operation System (MEMOs) for Blood Testing of Alzheimer's Disease

Advanced Science, EarlyView.
This work presents an automated and accessible point‐of‐care device, MEMOs, for the detection of exosomal Aβ42 protein, a potential blood biomarker for Alzheimer’s disease. MEMOs, with its automated operation workflow, minimizes hands‐on time and maintains high sensitivity in diagnosing AD, allowing non‐specialists to conduct tests at home and offering
Xiaoxue Fan, Xinyu Ye, Jiangrui Xu, Tianjiao Mao, Ruotong Zhang, Xinyuan Zhou, Christina C. K. Au Yeung, Chang Li, Raymond Chuen‐Chung Chang, Haisong Lin, Ho Cheung Shum   +10 more
wiley   +1 more source

A cluster-randomized trial of interventions for adolescent mental disorders in Zimbabwe. [PDF]

BMC Psychiatry
Beji-Chauke R, Simms V, Abas M, Muzariri K, Mavhu W, Mangenah C, Verhey R, Chiriseri E, Dambi JM, Araya R, Weiss HA, Cowan FM, Chibanda D.   +12 more
europepmc   +1 more source

Research in Mental Disorder [PDF]

, 1925
Judith Bannister, M. Saint Jean, J By
openalex   +1 more source

Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity

Advanced Science, EarlyView.
In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie, Runzhi Huang, Weijin Qian, Xinran Ding, Wei Zhang, Yixu Li, Jianyu Lu, Hanlin Sun, Yifan Liu, Yuntao Yao, Bingnan Lu, Minjuan Wu, Zhaofan Xia, Shizhao Ji   +13 more
wiley   +1 more source

Altered oral microbiome composition in mental disorders: a systematic review and meta-analysis. [PDF]

J Oral Microbiol
Cao D, Yang J, He Y, Zheng X, Li Y, Chen Y, Tu Y.   +6 more
europepmc   +1 more source

Mental and Respiratory Disorders following Epidemic Encephalitis [Troubles psychiques et respiratoires consécutifs a l'encéphalite épidémique]. (Bull. Soc. Clin. de Méd. Ment., November, 1922.) Roubenovitch, J., Barük and Bariety [PDF]

, 1927
J. S. Annandale
openalex   +1 more source