Results 11 to 20 of about 1,664,731 (339)

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó   +16 more
wiley   +1 more source

Hormonal and inflammatory signatures of different mood episodes in bipolar disorder: a large-scale clinical study

BMC Psychiatry, 2023
Background Bipolar disorder (BD) is characterized by intensive mood fluctuations. While hormones imbalance plays important role in the mood swings, it is unknown whether peripheral hormones profiles could differentiate the manic and depressive mood ...
Nan Lyu, Qian Zhao, Bingbing Fu, Jinhong Li, Han Wang, Fan Yang, Sitong Liu, Juan Huang, Xinwei Zhang, Ling Zhang, Rena Li   +10 more
doaj   +1 more source

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao, Bing Han, Cui‐Hong Qin, Xue‐Xiu Shi, Wen‐Jing Yun, Meng Wang, Bo Yuan, Tong‐Wen Sun, Hai‐Xu Wang   +8 more
wiley   +1 more source

To what extent does severity of loneliness vary among different mental health diagnostic groups: A cross-sectional study. [PDF]

, 2020
Loneliness is a common and debilitating problem in individuals with mental health disorders. However, our knowledge on severity of loneliness in different mental health diagnostic groups and factors associated with loneliness is poor, thus limiting the ...
Alasmawi, K, Lewis, G, Lloyd-Evans, B, Mann, F, Mezey, G, White, S   +5 more
core   +2 more sources

Multi-omics reveal microbial determinants impacting the treatment outcome of antidepressants in major depressive disorder

Microbiome, 2023
Background There is a growing body of evidence suggesting that disturbance of the gut-brain axis may be one of the potential causes of major depressive disorder (MDD).
Yaping Wang, Jingjing Zhou, Junbin Ye, Zuoli Sun, Yi He, Yingxin Zhao, Siyu Ren, Guofu Zhang, Min Liu, Peng Zheng, Gang Wang, Jian Yang   +11 more
doaj   +1 more source

Post-specific difference in mental health among medical staff in Beijing during COVID-19 epidemic: an online survey

Zhongguo gonggong weisheng, 2023
ObjectiveTo analyze the difference in mental health status among medical staff working at different posts in Beijing city during coronavirus disease 2019 (COVID-19) epidemic.
Yinqi LIU, Zhe WANG, Chunjie ZHANG
doaj   +1 more source

Revisiting the one in four: the prevalence of psychiatric disorder in the population of England 2000-2014 [PDF]

, 2020
Mental health problems are often said to affect one in four people in Britain, although with no consistent explanation of what the figure includes. We used three English national population surveys of psychiatric morbidity from 2000, 2007 and 2014 to ...
Drummond, McManus, McManus, Paul E. Bebbington, Sally McManus, Singleton   +5 more
core   +1 more source

Description and Predictive Factors of individual outcomes in a refugee camp based mental health intervention (Beirut, Lebanon) [PDF]

, 2013
There is little evidence on the effectiveness of services for the care of people with mental disorders among refugee populations. Médecins sans Frontières (MSF) has established a mental health centre in a mixed urban-refugee population in Beirut to ...
Alison Jones, Annick Antierens, EG Karam, L McDougal, Ludovic Rossel, M Porter, Mathieu Bastard, Pablo Melgar, Pierre Bastin, Richard Fielding, Z Hijazi   +10 more
core   +6 more sources

Spatial clustering of mental disorders and associated characteristics of the neighbourhood context in Malmö, Sweden, in 2001 [PDF]

, 2006
Study objective: Previous research provides preliminary evidence of spatial variations of mental disorders and associations between neighbourhood social context and mental health. This study expands past literature by (1) using spatial techniques, rather
Chaix, B., Chauvin, P., Kristersson, H., Leyland, A.H., Merlo, J., Råstam, L., Sabel, C.E.   +6 more
core   +4 more sources

Effects of escitalopram therapy on resting-state functional connectivity of subsystems of the default mode network in unmedicated patients with major depressive disorder

Translational Psychiatry, 2021
Antidepressants are often the first-line medications prescribed for patients with major depressive disorder (MDD). Given the critical role of the default mode network (DMN) in the physiopathology of MDD, the current study aimed to investigate the effects
Jian Cui, Yun Wang, Rui Liu, Xiongying Chen, Zhifang Zhang, Yuan Feng, Jingjing Zhou, Yuan Zhou, Gang Wang   +8 more
doaj   +1 more source