Results 11 to 20 of about 874,743 (311)

Mental disorders are not brain disorders [PDF]

Journal of Evaluation in Clinical Practice, 2013
AbstractAs advances in neuroscience and genetics reveal complex associations between brain structures, functions and symptoms of mental disorders, there have been calls for psychiatric classifications to be reconfigured, to conceptualize mental disorders as disorders of the brain.
openaire   +4 more sources

Post-specific difference in mental health among medical staff in Beijing during COVID-19 epidemic: an online survey

Zhongguo gonggong weisheng, 2023
ObjectiveTo analyze the difference in mental health status among medical staff working at different posts in Beijing city during coronavirus disease 2019 (COVID-19) epidemic.
Yinqi LIU, Zhe WANG, Chunjie ZHANG
doaj   +1 more source

Effects of escitalopram therapy on resting-state functional connectivity of subsystems of the default mode network in unmedicated patients with major depressive disorder

Translational Psychiatry, 2021
Antidepressants are often the first-line medications prescribed for patients with major depressive disorder (MDD). Given the critical role of the default mode network (DMN) in the physiopathology of MDD, the current study aimed to investigate the effects
Jian Cui, Yun Wang, Rui Liu, Xiongying Chen, Zhifang Zhang, Yuan Feng, Jingjing Zhou, Yuan Zhou, Gang Wang   +8 more
doaj   +1 more source

Risk factors for osteoporosis in chronic schizophrenia on long-term treatment with antipsychotics: a cross-sectional study

BMC Psychiatry, 2023
Background Little is known about the laboratory variable risks with bone mineral density (BMD) in patients with schizophrenia. This study was designed to fully investigate the related risk factors for decreased BMD in schizophrenia, as well as evaluate ...
Furu Liu, Ying Wu, Jindong Chen, Tianxiang Zou, Yue Qin, Ziwei Teng, Yuhan Su, Renrong Wu, Jing Huang   +8 more
doaj   +1 more source

The effects of childhood trauma on personality in unaffected first-degree relatives of patients with major depressive disorder

BMC Psychiatry, 2022
Abstrac Objectives This study aimed to preliminarily and exploratorily examine the associations between childhood trauma (CT), its subtypes, and personality traits among unaffected first-degree relatives (FDR, children, or siblings) of patients with ...
Yu-jie Wen, Qi-jing Bo, Wen-peng Hou, Zhen Mao, Feng Li, Fan He, Fang Dong, Xin Ma, Yi-lang Tang, Xian-bin Li, Chuan-yue Wang   +10 more
doaj   +1 more source

Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial

Translational Psychiatry
Working memory deficits are linked to irregularities in the dorsolateral prefrontal cortex (DLPFC) and the posterior parietal cortex (PPC) in schizophrenia, effective intervention strategies are lacking.
Wenpeng Hou, Fuchun Zhou, Qi Wang, Hang Li, Xiangqin Qin, Yushen Ding, Fang Dong, Qijing Bo, Anning Li, Liang Zhang, Zhenzhu Chen, Zhimin Wang, Xianbin Li, Jimmy Lee, Chuanyue Wang   +14 more
doaj   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Predicting antidepressant response via local-global graph neural network and neuroimaging biomarkers

npj Digital Medicine
Depressed mood and anhedonia, the core symptoms of major depressive disorder (MDD), are linked to dysfunction in the brain’s reward and emotion regulation circuits.
Rui Liu, Ximan Hou, Shuyu Liu, Yuan Zhou, Jingjing Zhou, Kaini Qiao, Han Qi, Ruinan Li, Zhi Yang, Ling Zhang, Jian Cui, Cheng Jin, Aihong Yu, Gang Wang   +13 more
doaj   +1 more source

Comprehensive analysis of circRNA expression profile and circRNA-miRNA-mRNA network susceptibility to very early-onset schizophrenia

Schizophrenia, 2023
To explore the potential role of circular RNAs (circRNAs) in children developing very early-onset schizophrenia (VEOS). Total RNA was extracted from the plasma samples of 10 VEOS patients and eight healthy controls. Expression profiles of circRNAs, micro
Huanhuan Huang, Jie Luo, Yanjie Qi, Yuanzhen Wu, Junhui Qi, Xiuping Yan, Gaoyang Xu, Fan He, Yi Zheng   +8 more
doaj   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source