Results 21 to 30 of about 4,798,446 (254)

Stratified medicine for mental disorders

open access: yesEuropean Neuropsychopharmacology, 2014
There is recognition that biomedical research into the causes of mental disorders and their treatment needs to adopt new approaches to research. Novel biomedical techniques have advanced our understanding of how the brain develops and is shaped by behaviour and environment. This has led to the advent of stratified medicine, which translates advances in
Schumann, G.   +45 more
openaire   +14 more sources

Comprehensive analysis of circRNA expression profile and circRNA-miRNA-mRNA network susceptibility to very early-onset schizophrenia

open access: yesSchizophrenia, 2023
To explore the potential role of circular RNAs (circRNAs) in children developing very early-onset schizophrenia (VEOS). Total RNA was extracted from the plasma samples of 10 VEOS patients and eight healthy controls. Expression profiles of circRNAs, micro
Huanhuan Huang   +8 more
doaj   +1 more source

Association between Mental Disorders and Subsequent Medical Conditions.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Persons with mental disorders are at a higher risk than the general population for the subsequent development of certain medical conditions. METHODS We used a population-based cohort from Danish national registries that included data on more
N. Momen   +37 more
semanticscholar   +1 more source

The effects of childhood trauma on personality in unaffected first-degree relatives of patients with major depressive disorder

open access: yesBMC Psychiatry, 2022
Abstrac Objectives This study aimed to preliminarily and exploratorily examine the associations between childhood trauma (CT), its subtypes, and personality traits among unaffected first-degree relatives (FDR, children, or siblings) of patients with ...
Yu-jie Wen   +10 more
doaj   +1 more source

WHO World Mental Health Surveys International College Student Project: Prevalence and Distribution of Mental Disorders

open access: yesJournal of Abnormal Psychology, 2018
Increasingly, colleges across the world are contending with rising rates of mental disorders, and in many cases, the demand for services on campus far exceeds the available resources.
R. Auerbach   +17 more
semanticscholar   +1 more source

Functional connectivity of the default mode network subsystems in patients with major depressive episodes with mixed features

open access: yesGeneral Psychiatry, 2022
Background The neuroimaging mechanism of major depressive episodes with mixed features (MMF) is not clear.Aims This study aimed to investigate the functional connectivity of the default mode network (DMN) subsystems among patients with MMF and patients ...
Jing Liu   +9 more
doaj   +1 more source

Increased risk of COVID‐19 infection and mortality in people with mental disorders: analysis from electronic health records in the United States

open access: yesWorld Psychiatry, 2020
Concerns have been expressed that persons with a pre‐existing mental disorder may represent a population at increased risk for COVID‐19 infection and with a higher likelihood of adverse outcomes of the infection, but there is no systematic research ...
QuanQiu Wang, Rong Xu, N. Volkow
semanticscholar   +1 more source

Optimization of measurement-based care (OMBC) for depression based on all-round and continuous assessment: rationale and protocol for a multicenter randomized control clinical trial

open access: yesTrials, 2022
Background Despite the recent findings presenting the benefits of measurement-based care (MBC) compared to treatment as usual (TAU), MBC is still not the standard of care used in clinical settings.
Jingjing Zhou   +6 more
doaj   +1 more source

Demographic, clinical and biochemical correlates of the length of stay for different polarities in Chinese inpatients with bipolar disorder: A real-world study

open access: yesFrontiers in Human Neuroscience, 2023
Introduction: Many patients with bipolar disorder (BD) need hospitalization, while the number of hospital beds for these patients is limited. Managing the length of stay (LOS) is an effective solution to this issue.
Wei Wang   +7 more
doaj   +1 more source

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