Results 31 to 40 of about 5,076,978 (312)

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Research review: A meta-analysis of the international prevalence and comorbidity of mental disorders in children between 1 and 7 years.

Journal of Child Psychology and Psychiatry and Allied Disciplines, 2020
BACKGROUND Children younger than 7 years can develop mental disorders that might manifest differently than in older children or adolescents. However, little is known about the prevalence of mental disorders at this early age.
M. Vasileva, R. Graf, T. Reinelt, U. Petermann, F. Petermann   +4 more
semanticscholar   +1 more source

CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani, Tsuyoshi Nakai, Yasuhiro Maeda, Reiko Ohdake, Atsuhiro Higashi, Toshiki Maeda, Ryunosuke Nagao, Sayuri Shima, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Hirohisa Watanabe   +11 more
wiley   +1 more source

High testosterone levels associated with elevated suicidal risk in male adolescents with depression

BMC Psychiatry
Background Adolescent suicide, as a public health issue, is becoming increasingly urgent, yet there remains a lack of effective objective biomarkers for identifying high-risk adolescents.
Han Wang, Nan Lyu, Juan Huang, Bingbing Fu, Lili Shang, Fan Yang, Ling Zhang, Qian Zhao   +7 more
doaj   +1 more source

Comprehensive analysis of circRNA expression profile and circRNA-miRNA-mRNA network susceptibility to very early-onset schizophrenia

Schizophrenia, 2023
To explore the potential role of circular RNAs (circRNAs) in children developing very early-onset schizophrenia (VEOS). Total RNA was extracted from the plasma samples of 10 VEOS patients and eight healthy controls. Expression profiles of circRNAs, micro
Huanhuan Huang, Jie Luo, Yanjie Qi, Yuanzhen Wu, Junhui Qi, Xiuping Yan, Gaoyang Xu, Fan He, Yi Zheng   +8 more
doaj   +1 more source

Comorbidity within mental disorders: a comprehensive analysis based on 145 990 survey respondents from 27 countries

Epidemiology and Psychiatric Sciences, 2020
Aims Epidemiological studies indicate that individuals with one type of mental disorder have an increased risk of subsequently developing other types of mental disorders.
J. Mcgrath, J. Mcgrath, J. Mcgrath, C. Lim, C. Lim, O. Plana-Ripoll, Y. Holtz, E. Agerbo, E. Agerbo, N. Momen, P. Mortensen, P. Mortensen, C. Pedersen, J. Abdulmalik, S. Aguilar-Gaxiola, A. Al-Hamzawi, J. Alonso, E. Bromet, R. Bruffaerts, B. Bunting, J. D. Almeida, G. Girolamo, Y. D. Vries, S. Florescu, O. Gureje, J. Haro, J. Haro, M. Harris, M. Harris, Chi‐yi Hu, E. Karam, N. Kawakami, A. Kiejna, V. Kovess-Masfety, S. Lee, Z. Mneimneh, F. Navarro-Mateu, R. Orozco, J. Posada-Villa, A. Roest, S. Saha, S. Saha, K. Scott, J. C. Stagnaro, D. Stein, Y. Torres, M. Viana, Yuval Ziv, Ronald C. Kessler, P. Jonge   +49 more
semanticscholar   +1 more source

Long COVID in People With Multiple Sclerosis and Related Disorders: A Multicenter Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu, Jiyeon Son, Lindsay McAlpine, Elizabeth L. S. Walker, Megan Dahl, Emily Song, Sugeidy Ferreira Brito, Katelyn Kavak, Kaho Onomichi, Amit Bar‐Or, Christopher Perrone, Claire S. Riley, Bianca Weinstock‐Guttman, Philip L. De Jager, Erin E. Longbrake, Zongqi Xia   +15 more
wiley   +1 more source

Shared and unique alterations of large-scale network connectivity in drug-free adolescent-onset and adult-onset major depressive disorder

Translational Psychiatry
Differences in clinical manifestations and biological underpinnings between Major Depressive Disorder (MDD) onset during adolescence and adulthood have been posited in previous studies, implying an influential role of age of onset (AOO) in the clinical ...
Ximan Hou, Rui Liu, Yuan Zhou, Lin Guan, Jingjing Zhou, Jing Liu, Mengqi Liu, Xiaofei Yuan, Yuan Feng, Xu Chen, Aihong Yu   +10 more
doaj   +1 more source

Plasma p‐tau181 as a Marker of Conversion to Alzheimer's Disease Dementia and Worsening in Cognitive Functions in Subjective Cognitive Decline and Mild Cognitive Impairment: A Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci, Assunta Ingannato, Chiara Crucitti, Silvia Bagnoli, Elisa Marcantelli, Sonia Padiglioni, Valentina Moschini, Carmen Morinelli, Laura Falsini, Sandro Sorbi, Valentina Berti, Benedetta Nacmias, Valentina Bessi   +12 more
wiley   +1 more source

The cost of mental disorders: a systematic review

Epidemiology and Psychiatric Sciences, 2020
Aims To identify and synthesise the literature on the cost of mental disorders. Methods Systematic literature searches were conducted in the databases PubMed, EMBASE, Web of Science, EconLit, NHS York Database and PsychInfo using key terms for cost and ...
M. Christensen, Carmen C. W. Lim, S. Saha, O. Plana-Ripoll, D. Cannon, F. Presley, Nanna Weye, N. Momen, H. Whiteford, K. Iburg, John J. McGrath   +10 more
semanticscholar   +1 more source