Results 31 to 40 of about 2,012,791 (358)

Common Mental Disorders

Kathmandu University Medical Journal, 2012
Common mental disorders are a group of distress states manifesting with anxiety, depressive and unexplained somatic symptoms typically encountered in community and primary care settings. Risk factors for these disorders are mainly lower socio-economic status, psychological illnesses, poor reproductive health, gender disadvantage and physical ill-health.
openaire   +3 more sources

Effect of transcranial direct current stimulation with concurrent cognitive performance targeting posterior parietal cortex vs prefrontal cortex on working memory in schizophrenia: a randomized clinical trial

Translational Psychiatry
Working memory deficits are linked to irregularities in the dorsolateral prefrontal cortex (DLPFC) and the posterior parietal cortex (PPC) in schizophrenia, effective intervention strategies are lacking.
Wenpeng Hou, Fuchun Zhou, Qi Wang, Hang Li, Xiangqin Qin, Yushen Ding, Fang Dong, Qijing Bo, Anning Li, Liang Zhang, Zhenzhu Chen, Zhimin Wang, Xianbin Li, Jimmy Lee, Chuanyue Wang   +14 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Predicting antidepressant response via local-global graph neural network and neuroimaging biomarkers

npj Digital Medicine
Depressed mood and anhedonia, the core symptoms of major depressive disorder (MDD), are linked to dysfunction in the brain’s reward and emotion regulation circuits.
Rui Liu, Ximan Hou, Shuyu Liu, Yuan Zhou, Jingjing Zhou, Kaini Qiao, Han Qi, Ruinan Li, Zhi Yang, Ling Zhang, Jian Cui, Cheng Jin, Aihong Yu, Gang Wang   +13 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Peripheral NMDAR subunits as predictors of working memory improvement in schizophrenia

Schizophrenia
Cognitive dysfunction is a defining characteristic impairing social functioning in schizophrenia (SZ). N-methyl-D-aspartate receptor (NMDAR) hypofunction may underlie these impairments.
Xiangqin Qin, Wenpeng Hou, Zhen Mao, Hang Li, Qi Wang, Yushen Ding, Lige Ge, Fuchun Zhou, Qijing Bo, Xianbin Li, Chuanyue Wang, Fang Dong   +11 more
doaj   +1 more source

Flood- and Weather-Damaged Homes and Mental Health: An Analysis Using England's Mental Health Survey [PDF]

, 2019
There is increasing evidence that exposure to weather-related hazards like storms and floods adversely affects mental health. However, evidence of treated and untreated mental disorders based on diagnostic criteria for the general population is limited ...
Cotton, J., Graham, H., McManus, S., White, P.   +3 more
core   +2 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Association of hypertension and depression with mortality: an exploratory study with interaction and mediation models

BMC Public Health
Background The association of hypertension and depression with mortality has not been fully understood. We aimed to explore the possible independent or joint association of hypertension and depression with mortality.
Huanhuan Huang, Fanchao Meng, Yanjie Qi, Xiuping Yan, Junhui Qi, Yuanzhen Wu, Yiwei Lin, Xu Chen, Fan He   +8 more
doaj   +1 more source

Mental Disorders Identification Applications Since Early Using Web-based Macromedia Flash Mx 2004 [PDF]

, 2006
The growing world of computer technology so that all the problems can be solved one way is to create a "The application of functional recognition of mental disorders since the early web-based using Macromedia Flash MX 2004" which with this application we
Melani Dewi Lusita, SKom, MMSI, Muhammad, M. (Muhammad)   +1 more
core