Results 91 to 100 of about 1,762,356 (302)

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

"Mothers as Candy Wrappers": Critical Infrastructure Supporting the Transition into Motherhood [PDF]

, 2019
Copyright © ACM. The transition into motherhood is a complicated and often unsupported major life disruption. To alleviate mental health issues and to support identity re-negotiation, mothers are increasingly turning to online mothers\u27 groups ...
Barkhuus, Louise, Britton, Lauren, Semaan, Bryan   +2 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Influence of mental effort on sound evaluations in virtual and real experimental environments

Frontiers in Virtual Reality
Psychoacoustic research increasingly relies on virtual reality (VR) to account for the complexity of acoustic scenarios and enhance the ecological validity of laboratory findings. However, recent studies suggest that virtual environments can alter mental
Hendrik Himmelein, Hendrik Himmelein, Markus von Berg, Markus von Berg, Christoph Pörschmann, Jochen Steffens, Jochen Steffens   +6 more
doaj   +1 more source

Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort [PDF]

, 2010
Cocoa flavanols (CF) positively influence physiological processes in ways that suggest their consumption may improve aspects of cognitive function. This study investigated the acute cognitive and subjective effects of CF consumption during sustained ...
Andrew B Scholey, Anthea L Milne, Crews WD, Crystal F Haskell, David O Kennedy, Engler MB, Evans SM, Faridi Z., Frei B., Gu L., Heiss C., Keppel G., Patel AK, Penelope J Morris, Rein D., Robbins R., Scholey A., Sorond FA, Spencer JPE, Spielberger CD, Stephen J French   +20 more
core   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Obstacles in Human Service Work with Teen Mothers [PDF]

, 2013
Research has shown that it is extremely beneficial for teen mothers to have support during their pregnancy and during their new experience of motherhood.
Casale, Chloe
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Mapping cognitive load profiles in realistic mathematics education: A study with aerospace engineering students

Jurnal Elemen
Although Realistic Mathematics Education (RME) promotes deeper conceptual learning, empirical evidence mapping different types of cognitive loads in university engineering mathematics is limited.
Rindu Alriavindra Funny, Fajar Khanif Rahmawati   +1 more
doaj   +1 more source