Results 71 to 80 of about 1,075,798 (302)
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Stories of Children, Youth, and Families’ Adaptation to Community Living in the First Year after Involvement with Children’s Residential Mental Health Programs [PDF]
, 2019 Twenty-two youth between the ages of 14 and 18 years old who were involved with residential programs from participating children’s mental health organizations in Southern Ontario, Canada during 2015 to 2017 participated in a study of adaptation to ...
Cameron, Gary, Frensch, Karen M.
core +1 more source
Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones +3 more
wiley +1 more source
It's our Community, Your Life, Everyone's Responsibility [PDF]
, 2018 The "Mind Your Mind" community initiative is about educating everyone to develop a basic level of "mental wellness" knowledge. Building mental health (or MH) knowledge will allow us to take care of our own mental health and talk more intelligently about ...
Terrill, Debbie, Terrill, Steve
core
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
The boundaries of mental health first aid [PDF]
Canadian Medical Association Journal, 2012 Sometimes it just takes a willingness to ask tough questions: “Are you suicidal? How would you kill yourself? Do you have the means? Have you attempted suicide in the past?” In other cases, the preferred protocol is to contact emergency services, while trying to reduce the level of distress ...
openaire +1 more source
Mental health first aid programs: a scoping review protocol
JBI Evidence Synthesis, 2020 This review aims to map mental health first aid programs, and identify the characteristics and participants of such programs and the contexts of their implementation.Mental health first aid is the help provided to a person developing a mental health problem or undergoing a mental health crisis.
Costa, Tiago +4 more
openaire +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source