Results 71 to 80 of about 1,056,673 (276)

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando   +13 more
wiley   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

Counting on U training to enhance trusting relationships and mental health literacy among business advisors: protocol for a randomised controlled trial

open access: yesBMC Psychiatry, 2022
Background Financial distress is thought to be a key reason why small-medium enterprise (SME) owners experience higher levels of mental health conditions compared with the broader population.
L. Saxon   +16 more
doaj   +1 more source

Stories of Children, Youth, and Families’ Adaptation to Community Living in the First Year after Involvement with Children’s Residential Mental Health Programs [PDF]

open access: yes, 2019
Twenty-two youth between the ages of 14 and 18 years old who were involved with residential programs from participating children’s mental health organizations in Southern Ontario, Canada during 2015 to 2017 participated in a study of adaptation to ...
Cameron, Gary, Frensch, Karen M.
core   +1 more source

Mutual help groups for mental health problems: A review of effectiveness studies [PDF]

open access: yes, 2008
This paper reviews empirical studies on whether participating in mutual help groups for people with mental health problems leads to improved psychological and social functioning. To be included, studies had to satisfy four sets of criteria, covering: (1)
Barker, C, Humphreys, K, Pistrang, N
core   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Evaluation of the Aboriginal and Torres Strait Islander Mental Health First Aid Program

open access: yesAustralian and New Zealand Journal of Public Health, 2021
Objective: This study reports findings from an uncontrolled evaluation of a course designed to educate participants in how to recognise and respond to mental health problems until professional help is received.
Andrew Day   +4 more
doaj   +1 more source

It's our Community, Your Life, Everyone's Responsibility [PDF]

open access: yes, 2018
The "Mind Your Mind" community initiative is about educating everyone to develop a basic level of "mental wellness" knowledge. Building mental health (or MH) knowledge will allow us to take care of our own mental health and talk more intelligently about ...
Terrill, Debbie, Terrill, Steve
core  

Mental health first aid for health-care workers during crises [PDF]

open access: bronze, 2023
Jenny Segalovich   +2 more
openalex   +1 more source

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow   +6 more
wiley   +1 more source

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