Results 71 to 80 of about 1,056,673 (276)
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando +13 more
wiley +1 more source
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Background Financial distress is thought to be a key reason why small-medium enterprise (SME) owners experience higher levels of mental health conditions compared with the broader population.
L. Saxon +16 more
doaj +1 more source
Stories of Children, Youth, and Families’ Adaptation to Community Living in the First Year after Involvement with Children’s Residential Mental Health Programs [PDF]
Twenty-two youth between the ages of 14 and 18 years old who were involved with residential programs from participating children’s mental health organizations in Southern Ontario, Canada during 2015 to 2017 participated in a study of adaptation to ...
Cameron, Gary, Frensch, Karen M.
core +1 more source
Mutual help groups for mental health problems: A review of effectiveness studies [PDF]
This paper reviews empirical studies on whether participating in mutual help groups for people with mental health problems leads to improved psychological and social functioning. To be included, studies had to satisfy four sets of criteria, covering: (1)
Barker, C, Humphreys, K, Pistrang, N
core +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source
Evaluation of the Aboriginal and Torres Strait Islander Mental Health First Aid Program
Objective: This study reports findings from an uncontrolled evaluation of a course designed to educate participants in how to recognise and respond to mental health problems until professional help is received.
Andrew Day +4 more
doaj +1 more source
It's our Community, Your Life, Everyone's Responsibility [PDF]
The "Mind Your Mind" community initiative is about educating everyone to develop a basic level of "mental wellness" knowledge. Building mental health (or MH) knowledge will allow us to take care of our own mental health and talk more intelligently about ...
Terrill, Debbie, Terrill, Steve
core
Mental health first aid for health-care workers during crises [PDF]
Jenny Segalovich +2 more
openalex +1 more source
Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow +6 more
wiley +1 more source

