Results 111 to 120 of about 2,527,419 (307)

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

open access: yesAdvanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao   +19 more
wiley   +1 more source

Social media and mental harms under the Digital Services Act

open access: yesInternet Policy Review
Numerous empirical studies indicate that social media use is correlated with, and sometimes might be causing, mental harms like addiction, anxiety and depression, or lowering of cognitive abilities. In 2023, the European Parliament called on the European
Przemysław Pałka, Ewa Ilczuk
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Child and Adolescent Mental Health In-patient Unit, Merlin Park University Hospital, Approved Centre Inspection Report 27-29 October 2015

open access: yes, 2016
Section 51 (1) (a) of the Mental Health Act (2001). States that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and inspect any
Mental Health Commission (MHC)
core  

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang   +11 more
wiley   +1 more source

Mental Health Classification Using Machine Learning with PCA and Logistics Regression Approaches for Decision Making

open access: yesEngineering Proceedings
Mental health statistics come with numerous challenges, beginning with data integrity. Ensuring data accuracy and reliability is essential, especially if these datasets are to be used for advanced analysis or research.
Hendra Hendra   +2 more
doaj   +1 more source

Centre for Mental Health Care & Recovery, Bantry General Hospital, Approved Centre Inspection Report 22-23 October 2015

open access: yes, 2015
Section 51 (1) (a) of the Mental Health Act (2001). States that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and inspect any
Mental Health Commission (MHC)
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Impact of three miniplate configurations on mental nerve integrity in parasymphyseal mandibular fractures: a blinded randomized trial

open access: yesBMC Oral Health
Objectives To assess the mental nerve’s functional integrity after parasymphyseal mandibular fracture fixation using three different miniplates configurations.
Reem M. Ismail   +4 more
doaj   +1 more source

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