Results 151 to 160 of about 762,329 (306)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Long-term consequences of childhood emotional abuse in mothers on parental load and child mental health

Acta Psychologica
Background: Childhood emotional maltreatment can be associated with long-term consequences on mental health. In addition, transgenerational transmission of adverse childhood experiences to the next generation can occur and thus have an impact on the ...
Katharina Rost, Emily Gossmann, Jörg M. Fegert, Ute Ziegenhain, Franziska Köhler-Dauner   +4 more
doaj   +1 more source

An attempt at mental load quantification in some mental tasks

Review of psychology, 2002
In most mental load studies there is a problem of mental load assessment and its diferentation, which makes the attribution of changes in dependent variables difficult or impossible. The aim of this study was to indirectly quantify mental load in counting backward tasks (assessed on Borg's scale), by use of fitted regression line between Fitts' tapping
Slavić, Ana, Manenica, Ilija
openaire   +3 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

An Implanted Tooth That Can Feel

Advanced Science, EarlyView.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao, Zhenhua Wu, Jiwei Sun, Ke Song, Jiayi Li, Yujin Li, Wenqi Chen, Hanyu Li, Shue Li, Cheng Yang, Silin Liu, Yunyun Han, Bin Su, Yumei Ding   +13 more
wiley   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Bioinspired Hierarchical Architecture with Water Transport Channels for Strong Adhesion at the Sweating Interface

Advanced Science, EarlyView.
To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...
Jieliang Zhao, Yu Xiang, Heng Wang, Huiqing Xu, Zhong Liu, Lulu Liang, Fengwen Jiang, Xuemei Chen, Wenzhong Wang, Chenqing Liu, Guodong Liu, Shaoze Yan, Xu Hou   +12 more
wiley   +1 more source

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

Advanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini, Claudia Alvarez‐Martin, Paula Angermair‐Barkai, Olivier Penacchio, Marc Paz, Matthew Pelowski, Dan Dediu, Antoni Rodriguez‐Fornells, Xim Cerda‐Company   +8 more
wiley   +1 more source

Experienced cognitive load in the emergency department. A prospective study.

PLoS ONE
Background and importanceThe emergency department (ED) is a hectic place, where many critically ill patients are treated. For residents working in the ED, this environment may be demanding.ObjectivesThe aim of this study was to investigate the [1 ...
Yael Appelboom, Yvonne Groenen, Dirk Notten, Anique De Bruin, Jacqueline Buijs, Harm R Haak, Hella F Broggreve, Lars Lambriks, Patricia M Stassen   +8 more
doaj   +1 more source