Results 191 to 200 of about 17,010,551 (310)

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Using a mental model approach to undercut the effects of exposure to mRNA vaccination misconceptions: Two randomized trials. [PDF]

Proc Natl Acad Sci U S A
Jamieson KH, Gibson LA, Jamieson PE, Patterson S.   +3 more
europepmc   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Evaluation of Large Language Models to Detect Team Mental Model Misalignments During Cardiac Surgery. [PDF]

Hamlyn Symp Med Robot
Dias RD, Unhelkar V, Shann K, Weinberg A, Rance G, Srey R, O'Gara P, Shapeton A, Robertson JM, Borges P, Verly R, Mendu S, Zenati MA.   +12 more
europepmc   +1 more source

ODMH forensic manual

, 2003
[Rev.].; Title from PDF cover (viewed Sept. 12, 2006); at head of title: Ohio Department of Mental Health ...; Effective date: February 25, 2003.; Harvested from the web on 9/12/06Introduction and overview -- The criminal courts of Ohio -- Community ...
Ohio. Dept. of Mental Health. Office of Forensic Services
core  

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Many Minds, One Model: Exploring Decision Making of an Undergraduate Medicine Competency Committee Using the Construct of a Shared Mental Model. [PDF]

Perspect Med Educ
Mickleborough T, Tait GR, Mylopoulos M, Kulasegaram KM.   +3 more
europepmc   +1 more source

A Strategy Study on Risk Communication of Pandemic Influenza: A Mental Model Study of College Students in Beijing. [PDF]

Risk Manag Healthc Policy, 2020
Yang H, Pang X, Zheng B, Wang L, Wang Y, Du S, Lu X.   +6 more
europepmc   +1 more source

Department of Psychiatry, Waterford Regional Hospital Focused Inspection Report, 13 - 14 July 2016

, 2016
The principal functions of the Mental Health Commission are to promote, encourage and foster the establishment and maintenance of high standards and good practices in the delivery of mental health services and to take all reasonable steps to protect the ...
Mental Health Commission
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source