Results 211 to 220 of about 2,446,659 (352)

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Identification of transdiagnostic phenomena among patients, the general population, relatives, and mental health professionals using topic modeling techniques. [PDF]

Front Psychol
Vancappel A, Kazzi H, Zgaya-Biau H, Saur R, Fourel E, Courtois R, Tapia G, Kosinski T, Carré A, Bortolon C, Marteau-Chasserieau F, Romo L, Baeyens C, Morvan Y, Besche-Richard C, El-Hage W.   +15 more
europepmc   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

The performance of mind: from movement, mental states, and consciousness. [PDF]

Front Psychol
Cheron G, Cebolla AM.
europepmc   +1 more source

Conceptual and Ethical Problems in the Mental Capacity Act 2005: An Interrogation of the Assessment Process [PDF]

, 2015
David Gibson
openalex   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Correction: Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mouse model of Alzheimer's disease. [PDF]

Alzheimers Res Ther
Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, Wei X, Yin H.   +11 more
europepmc   +1 more source

Global Research on Pandemics or Epidemics and Mental Health: A Natural Language Processing Study [PDF]

Xin Ye, Xinfeng Wang, Hugo You‐Hsien Lin   +2 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Minding the moving self: the centrality of body movement in the neurodynamics of the self and psychotherapeutic implications. [PDF]

Front Psychiatry
Vaisvaser S.
europepmc   +1 more source