Results 81 to 90 of about 2,259,944 (347)

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Neurobiology of Disease, 2011
Emerging evidence points to reactive glia as a pivotal factor in Parkinson's disease (PD) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of basal ganglia injury, but whether astrocytes and microglia activation may exacerbate
F. L'Episcopo, C. Tirolo, N. Testa, S. Caniglia, M.C. Morale, C. Cossetti, P. D'Adamo, E. Zardini, L. Andreoni, A.E.C. Ihekwaba, P.A. Serra, D. Franciotta, G. Martino, S. Pluchino, B. Marchetti   +14 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

Arthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

MORPHOFUNCTIONAL AND PSYCHOPHYSIOLOGICAL FEATURES IN CHILDREN WITH INTELLECTUAL DISORDERS

Вестник Кемеровского государственного университета, 2017
The article studies morphofunctional and psychophysiological features in children with mental disabilities. The research features 7–9-year-old children, both male and female, with different central nervous system diseases (various degrees of mental ...
Nina G. Blinova, Nataliya N. Koshko, Ramil M. Akbirov   +2 more
doaj   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0

Journal of Lipid Research, 1976
A hitherto undescribed sphingomyelinase (sph'ase 7.4) of human brain has been studied in crude and partially purified (3- to 4- fold) extracts of grey matter, and compared to the known sphingomyelinase with an acid pH optimum (sph'ase 5.0).
B G Rao, Dr M W Spence
doaj   +1 more source

Pembelajaran Tari Kreasi Anak Tuna Grahita Ringan Melalui Proses Imitatif [PDF]

, 2018
Creation Dance is a cultivation of new dance work made in accordance with the needs of the consumption of the audience and is the result of creative ideas of the choreographer, especially in this study, the created creations dance is the result of the ...
Amalia, R. D. (Rizka), Sari, D. I. (Dyan), Sudigdo, A. (Anang)   +2 more
core   +2 more sources

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

BMC Neuroscience, 2010
BackgroundRett syndrome (RTT), a common cause of mental retardation in girls, is associated with mutations in the MECP2 gene. Most human cases of MECP2 mutation in girls result in classical or variant forms of RTT.
Garilyn Jentarra, Shannon L Olfers, S. G. Rice, N. Srivastava, G. Homanics, M. Blue, S. Naidu, V. Narayanan   +7 more
semanticscholar   +1 more source

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi, Maria Sabrina Sarto   +7 more
wiley   +1 more source

Epilepsy and Mental Retardation

Pediatric Neurology Briefs, 1991
The cumulative risk of seizures and epilepsy was studied in a prospectively identified cohort of 221 children with mental retardation born between 1951 and 1955 in Aberdeen, Scotland and reported from the Montefiore-Einstein Epilepsy Management Center ...
J Gordon Millichap
doaj   +1 more source

Fragile X syndrome. [PDF]

, 2014
Fragile X Syndrome (FXS) is a genetic disease due to a CGG trinucleotide expansion, named full mutation (greater than 200 CGG repeats), in the fragile X mental retardation 1 gene locus Xq27.3; which leads to an hypermethylated region in the gene promoter
Ayala-Zapata, Sebastián, Forero-Forero, Jose Vicente, González-Teshima, Laura Yuriko, Hagerman, Randi, Saldarriaga, Wilmar, Tassone, Flora   +5 more
core   +1 more source