Results 161 to 170 of about 2,307,599 (364)

Methylphenidate, but not citalopram, decreases impulsive choice in rats performing a temporal discounting task

open access: yesFrontiers in Psychiatry
IntroductionDrugs targeting monoamine systems remain the most common treatment for disorders with impulse control impairments. There is a body of literature suggesting that drugs affecting serotonin reuptake and dopamine reuptake can modulate distinct ...
Miranda F. Koloski   +7 more
doaj   +1 more source

Stress and psychological wellbeing in local humanitarian workers in Colombia working for a local non-governmental organization : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Albany, New Zealand [PDF]

open access: yes, 2008
This study examined the differences in stress and psychological wellbeing in 75 local humanitarian personnel (70 females and 5 males, median age = 30.7) from "Fundacion CC", local non-governmental organisation from Medellin, Colombia, who worked either ...
Abad, Jaime
core  

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

open access: yesAdvanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman   +3 more
wiley   +1 more source

Minority-specific Determinants of Mental Well-being Among Lesbian, Gay and Bisexual Youth [PDF]

open access: yes, 2008
This study discusses the impact of stress specific to being lesbian, gay, or bisexual (LGB), measured by means of the concepts of stigma consciousness and internalized homonegativity, on the mental well-being of LGB youth.
Cox, Nele   +3 more
core  

Evaluating resilience in response to COVID-19 pandemic stressors among veteran mental health outpatients.

open access: hybrid, 2022
Craig A. Marquardt   +10 more
openalex   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

open access: yesAdvanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

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