Results 131 to 140 of about 4,861,087 (314)

Centre for Mental Health Care & Recovery, Bantry General Hospital, Approved Centre Inspection Report 22-23 October 2015

open access: yes, 2015
Section 51 (1) (a) of the Mental Health Act (2001). States that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and inspect any
Mental Health Commission (MHC)
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Peritraumatic reactions during sexual assault: associations with assault characteristics and mental health

open access: yesEuropean Journal of Psychotraumatology
Background: Peritraumatic reactions during sexual assault are central to societal rape stereotypes and may play a role in post-trauma mental health. Nevertheless, existing research is limited.
Isabel Kreis   +5 more
doaj   +1 more source

St Patrick’s University Hospital Mental Health Commission Approved centre Inspection Report 8-11 November 2016

open access: yes, 2017
Section 51(1)(a) of the Mental Health Act 2001 (the 2001 Act) states that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and ...
Mental Health Commission (MHC)
core  

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Lakeview Unit, Naas General Hospital Mental Health Commission Approved Centre Inspection Report 1-4 August 2017

open access: yes, 2018
Section 51(1)(a) of the Mental Health Act 2001 (the 2001 Act) states that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and ...
Mental Health Commission (MHC)
core  

The Mind From Within: Visceral Roots of Human Cognition

open access: yesAdvanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti   +1 more
wiley   +1 more source

Revealing the psychopathological pathway linking trauma to post-traumatic stress disorder: longitudinal network approach

open access: yesBJPsych Open
The present study investigated the psychopathological processes of post-traumatic stress disorder (PTSD) following the network approach to psychopathology.
Chen Chen   +4 more
doaj   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

open access: yesAdvanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

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