Results 121 to 130 of about 41,849 (302)

INSTITUTIONAL Change as Cultural Change. An Illustration by Chinese Postsocialist Transformation [PDF]

open access: yes
Culture of a society reflects its social values. So, through Chinese experience, we want to show that institutional change is not only an economic or a political process but fundamentally a cultural one.
EL KAROUNI, Ilyess
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Diagnosing Malta's condition in the novel [PDF]

open access: yes, 2011
Throughout the decades Maltese literature has reflected the Mediterranean environment to determine its influence on character. The use of harbour cities (like Birgu and Valletta) in different Maltese novels reflects the social behaviour of the ...
Briffa, Charles
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Mongolians: who are we?

open access: yesНовые исследования Тувы, 2016
Article defines the main characteristics adjacent to national mentalities, thinking and behavior of Mongolians. Their link to geographic, climatic, geopolitical, historic-cultural factors is being defined. 15 basic characteristics are named.
Coohu Hinayat
doaj  

CULTURE AND CORRUPTION [PDF]

open access: yes
National culture and the organization's management are interdependent systems of values, which generate human performances that can reach levels of excellence.
Mihut Ioan
core  

Home - About - Disclaimer - Privacy