Results 101 to 110 of about 41,849 (302)

CONSIDERATII ASUPRA UNOR SINTAGME REFERITOARE LA FACTORUL UMAN [PDF]

open access: yes
Economic and social development is accompanied by a series of conceptions that sustains all the fields of activity. Like the human society the economic activities are subject to changes, based on theories that argue the role, the importance and the place
Constantin ROSCA, Doina ROSCA
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Autonomy of the family in the modern world

open access: yesHoryzonty Wychowania, 2017
RESEARCH OBJECTIVE: The purpose of this article is to understand autonomy of the family in the ‘modern’ world by locating the family in the historical changes that led to its present form.
Nidhi Gulati
doaj  

Gangguan Mental (Mental Disorders)

open access: yesStudent Research Journal
Mental disorders are health conditions that affect a person's thoughts, emotions and behavior, often having a significant impact on the sufferer's daily functioning and quality of life. This research aims to examine various types of mental disorders, causal factors, and effective treatment methods.
null Kevin Vitoasmara   +4 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Professional Training of Human Resources [PDF]

open access: yes
Each organization has a human capital which resides in the knowledge and experience of its own employees, in their professional competence. For the purpose of using this capital as efficiently as possible in the process of carrying out working tasks, it ...
Mioara NEAMTU
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy