Results 101 to 110 of about 9,274 (253)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Vickers (Brian) ed Occult and Scientific mentalities in the Renaissance
, 1985 Lion Antoine. Vickers (Brian) ed Occult and Scientific mentalities in the Renaissance. In: Archives de sciences sociales des religions, n°60/2, 1985.
Lion, Antoine
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Teachers's mentalities in human rights education for children : What teachers do, and why
, 2018 Background: Educating children about human rights is an important step toward strengthening human rights in the global society. Teachers play a crucial role in the enactment of this education.
Isenström, Lisa,
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
‘Bringing it all back home’: mentalities, models and the historical study of religions
, 2014 If historians of mentalities are studying cultural models of the past, the cognitive historians of religions are in their turn studying religious model.
Sjöblom, Tom
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Structural Equation Modeling of Attitudes toward Marriage Based on Emotional Regulation and Schema Mode [PDF]
تحقیقات نظام سلامتBackground: The present study aimed to investigate the attitude towards marriage based on schema mentalities with emphasis on the mediating role of interpersonal emotional regulation in students.
Nahid Mikelani +3 more
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Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
ЦЕННОСТИ И АНТИЦЕННОСТИ В СОВРЕМЕННЫХ БРИТАНСКИХ И АВАРСКИХ РАССКАЗАХ / VALUES AND DISVALUES IN MODERN BRITISH AND AVAR STORIES / VALORI ŞI NON-VALORI ÎN POVESTIRILE MODERNE BRITANICE ŞI AVARE [PDF]
Studii si Cercetari Filologice: Seria Limbi Straine Aplicate, 2013 The article highlights linguocultural peculiarities of contemporary British and Avar ethnicities. The comparative study of nuclear and periphery values contribute to creation and interpretation of universal/ specific features of the given mentalities ...
Haibat Kadachieva
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